Acetyldigitoxin
Acetyldigitoxin may decrease the cardiotoxic activities of Letrozole.
Amiodarone
The metabolism of Letrozole can be decreased when combined with Amiodarone.
Ancestim
The risk or severity of cytotoxicity can be increased when Ancestim is combined with Letrozole.
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Apalutamide
The serum concentration of Letrozole can be decreased when it is combined with Apalutamide.
Aprepitant
The serum concentration of Letrozole can be increased when it is combined with Aprepitant.
Artesunate
The serum concentration of the active metabolites of Artesunate can be reduced when Artesunate is used in combination with Letrozole resulting in a loss in efficacy.
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Atazanavir
The metabolism of Letrozole can be decreased when combined with Atazanavir.
Atomoxetine
The metabolism of Letrozole can be decreased when combined with Atomoxetine.
Bevacizumab
Bevacizumab may increase the cardiotoxic activities of Letrozole.
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Bevacizumab-Awwb
Bevacizumab may increase the cardiotoxic activities of Letrozole.
Boceprevir
The metabolism of Letrozole can be decreased when combined with Boceprevir.
Bortezomib
The metabolism of Letrozole can be decreased when combined with Bortezomib.
Bosentan
The serum concentration of Letrozole can be decreased when it is combined with Bosentan.
Cabazitaxel
The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Letrozole.
Carbamazepine
The metabolism of Letrozole can be increased when combined with Carbamazepine.
Ceritinib
The serum concentration of Letrozole can be increased when it is combined with Ceritinib.
Clarithromycin
The metabolism of Letrozole can be decreased when combined with Clarithromycin.
Clemastine
The metabolism of Letrozole can be decreased when combined with Clemastine.
Clotrimazole
The metabolism of Letrozole can be decreased when combined with Clotrimazole.
Cobicistat
The metabolism of Letrozole can be decreased when combined with Cobicistat.
Conivaptan
The serum concentration of Conivaptan can be increased when it is combined with Letrozole.
Crizotinib
The metabolism of Letrozole can be decreased when combined with Crizotinib.
Cyclophosphamide
Cyclophosphamide may increase the cardiotoxic activities of Letrozole.
Cyclophosphamide Anhydrous
Cyclophosphamide may increase the cardiotoxic activities of Letrozole.
Cyclosporine
The metabolism of Letrozole can be decreased when combined with Cyclosporine.
Dabrafenib
The serum concentration of Letrozole can be decreased when it is combined with Dabrafenib.
Darunavir
The metabolism of Letrozole can be decreased when combined with Darunavir.
Dasatinib
The serum concentration of Letrozole can be increased when it is combined with Dasatinib.
Dasatinib Anhydrous
The serum concentration of Letrozole can be increased when it is combined with Dasatinib.
Deferasirox
The serum concentration of Letrozole can be decreased when it is combined with Deferasirox.
Delavirdine
The metabolism of Letrozole can be decreased when combined with Delavirdine.
Deslanoside
Deslanoside may decrease the cardiotoxic activities of Letrozole.
Digitoxin
Digitoxin may decrease the cardiotoxic activities of Letrozole.
Digoxin
Digoxin may decrease the cardiotoxic activities of Letrozole.
Dihydroergotamine
The metabolism of Letrozole can be decreased when combined with Dihydroergotamine.
Diltiazem
The metabolism of Letrozole can be decreased when combined with Diltiazem.
Docetaxel
The risk or severity of adverse effects can be increased when Docetaxel is combined with Letrozole.
DOCETAXEL ANHYDROUS
The risk or severity of adverse effects can be increased when Docetaxel is combined with Letrozole.
Doxycycline
The metabolism of Letrozole can be decreased when combined with Doxycycline.
Doxycycline Anhydrous
The metabolism of Letrozole can be decreased when combined with Doxycycline.
Dronedarone
The metabolism of Letrozole can be decreased when combined with Dronedarone.
Enzalutamide
The serum concentration of Letrozole can be decreased when it is combined with Enzalutamide.
Erythromycin
The metabolism of Letrozole can be decreased when combined with Erythromycin.
Fluconazole
The metabolism of Letrozole can be decreased when combined with Fluconazole.
Fluvoxamine
The metabolism of Letrozole can be decreased when combined with Fluvoxamine.
Fosamprenavir
The metabolism of Letrozole can be decreased when combined with Fosamprenavir.
Fosaprepitant
The serum concentration of Letrozole can be increased when it is combined with Fosaprepitant.
Fosphenytoin
The metabolism of Letrozole can be increased when combined with Fosphenytoin.
Fusidate
The serum concentration of Letrozole can be increased when it is combined with Fusidic Acid.
Fusidic Acid
The serum concentration of Letrozole can be increased when it is combined with Fusidic Acid.
Hypoxis hemerocallidea root extract
The serum concentration of Letrozole can be decreased when it is combined with St. John's Wort.
Idelalisib
The metabolism of Letrozole can be decreased when combined with Idelalisib.
Imatinib
The metabolism of Letrozole can be decreased when combined with Imatinib.
Indinavir
The metabolism of Letrozole can be decreased when combined with Indinavir.
INDINAVIR ANHYDROUS
The metabolism of Letrozole can be decreased when combined with Indinavir.
Isavuconazole
The serum concentration of Letrozole can be increased when it is combined with Isavuconazole.
Isavuconazonium
The metabolism of Letrozole can be decreased when combined with Isavuconazonium.
Isradipine
The metabolism of Letrozole can be decreased when combined with Isradipine.
Itraconazole
The metabolism of Letrozole can be decreased when combined with Itraconazole.
Ivacaftor
The serum concentration of Letrozole can be increased when it is combined with Ivacaftor.
Ketoconazole
The metabolism of Letrozole can be decreased when combined with Ketoconazole.
Lopinavir
The metabolism of Letrozole can be decreased when combined with Lopinavir.
Lovastatin
The metabolism of Letrozole can be decreased when combined with Lovastatin.
Luliconazole
The serum concentration of Letrozole can be increased when it is combined with Luliconazole.
Lumacaftor
The metabolism of Letrozole can be increased when combined with Lumacaftor.
Methadone
The serum concentration of Methadone can be increased when it is combined with Letrozole.
Mifepristone
The serum concentration of Letrozole can be increased when it is combined with Mifepristone.
Mitotane
The serum concentration of Letrozole can be decreased when it is combined with Mitotane.
Nefazodone
The metabolism of Letrozole can be decreased when combined with Nefazodone.
Nelfinavir
The metabolism of Letrozole can be decreased when combined with Nelfinavir.
Netupitant
The serum concentration of Letrozole can be increased when it is combined with Netupitant.
Nevirapine
The metabolism of Letrozole can be increased when combined with Nevirapine.
Nicotine
The metabolism of Letrozole can be decreased when combined with Nicotine.
Nicotine Polacrilex
The metabolism of Letrozole can be decreased when combined with Nicotine.
Nilotinib
The metabolism of Letrozole can be decreased when combined with Nilotinib.
Olaparib
The metabolism of Letrozole can be decreased when combined with Olaparib.
Osimertinib
The serum concentration of Letrozole can be increased when it is combined with Osimertinib.
Ouabain
Ouabain may decrease the cardiotoxic activities of Letrozole.
Ovine Digoxin Immune Fab
Digoxin Immune Fab (Ovine) may decrease the cardiotoxic activities of Letrozole.
Paclitaxel
The risk or severity of adverse effects can be increased when Paclitaxel is combined with Letrozole.
Palbociclib
The serum concentration of Letrozole can be increased when it is combined with Palbociclib.
Pentobarbital
The metabolism of Letrozole can be increased when combined with Pentobarbital.
Phenobarbital
The metabolism of Letrozole can be increased when combined with Phenobarbital.
Phenytoin
The metabolism of Letrozole can be increased when combined with Phenytoin.
Posaconazole
The metabolism of Letrozole can be decreased when combined with Posaconazole.
Primidone
The metabolism of Letrozole can be increased when combined with Primidone.
Proscillaridin
Proscillaridin may decrease the cardiotoxic activities of Letrozole.
Ranolazine
The metabolism of Letrozole can be decreased when combined with Ranolazine.
Rifabutin
The metabolism of Letrozole can be increased when combined with Rifabutin.
Rifampin
The metabolism of Letrozole can be increased when combined with Rifampicin.
Rifapentine
The metabolism of Letrozole can be increased when combined with Rifapentine.
Rucaparib
The metabolism of Letrozole can be decreased when combined with Rucaparib.
Saquinavir
The metabolism of Letrozole can be decreased when combined with Saquinavir.
Saquinavir Mesylate
The metabolism of Letrozole can be decreased when combined with Saquinavir.
Sarilumab
The therapeutic efficacy of Letrozole can be decreased when used in combination with Sarilumab.
Sildenafil
The metabolism of Letrozole can be decreased when combined with Sildenafil.
Siltuximab
The serum concentration of Letrozole can be decreased when it is combined with Siltuximab.
Simeprevir
The serum concentration of Letrozole can be increased when it is combined with Simeprevir.
ST. JOHN'S WORT EXTRACT
The serum concentration of Letrozole can be decreased when it is combined with St. John's Wort.
Sulfisoxazole
The metabolism of Letrozole can be decreased when combined with Sulfisoxazole.
Tamoxifen
The serum concentration of Letrozole can be decreased when it is combined with Tamoxifen.
Telaprevir
The metabolism of Letrozole can be decreased when combined with Telaprevir.
Telithromycin
The metabolism of Letrozole can be decreased when combined with Telithromycin.
Ticlopidine
The metabolism of Letrozole can be decreased when combined with Ticlopidine.
Tocilizumab
The serum concentration of Letrozole can be decreased when it is combined with Tocilizumab.
Trastuzumab
Trastuzumab may increase the cardiotoxic activities of Letrozole.
Vemurafenib
The serum concentration of Letrozole can be decreased when it is combined with Vemurafenib.
Venlafaxine
The metabolism of Letrozole can be decreased when combined with Venlafaxine.
Verapamil
The metabolism of Letrozole can be decreased when combined with Verapamil.
Voriconazole
The metabolism of Letrozole can be decreased when combined with Voriconazole.
Ziprasidone
The metabolism of Letrozole can be decreased when combined with Ziprasidone.
