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Ruxolitinib Interaction with other Drugs


Ruxolitinib is a kinase inhibitor, prescribed for high-risk myelofibrosis.

Ruxolitinib Interaction with 175 drugs. Find out more in the list below:

Acebutolol


Ruxolitinib may increase the bradycardic activities of Acebutolol.

Acetyldigitoxin


Acetyldigitoxin may decrease the cardiotoxic activities of Ruxolitinib.

Amiodarone


The serum concentration of Ruxolitinib can be increased when it is combined with Amiodarone.

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Ancestim


The risk or severity of cytotoxicity can be increased when Ancestim is combined with Ruxolitinib.

Anhydrous Tacrolimus


Tacrolimus may increase the immunosuppressive activities of Ruxolitinib.

Anthrax immune globulin, human


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Anthrax immune globulin human.

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Apalutamide


The serum concentration of Ruxolitinib can be decreased when it is combined with Apalutamide.

Aprepitant


The serum concentration of Ruxolitinib can be increased when it is combined with Aprepitant.

Atazanavir


The serum concentration of Ruxolitinib can be increased when it is combined with Atazanavir.

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Atenolol


Ruxolitinib may increase the bradycardic activities of Atenolol.

Atomoxetine


The metabolism of Ruxolitinib can be decreased when combined with Atomoxetine.

BCG Vaccine


The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Ruxolitinib.

BCG, Live, Connaught Strain


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Bacillus calmette-guerin substrain connaught live antigen.

BCG, Live, Tice Strain


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Bacillus calmette-guerin substrain tice live antigen.

Bendroflumethiazide


Ruxolitinib may increase the bradycardic activities of Bendroflumethiazide.

Beractant


Ruxolitinib may increase the bradycardic activities of Beractant.

Betaxolol


Ruxolitinib may increase the bradycardic activities of Betaxolol.

Bevacizumab


Bevacizumab may increase the cardiotoxic activities of Ruxolitinib.

Bevacizumab-Awwb


Bevacizumab may increase the cardiotoxic activities of Ruxolitinib.

Bisoprolol


Ruxolitinib may increase the bradycardic activities of Bisoprolol.

Boceprevir


The serum concentration of Ruxolitinib can be increased when it is combined with Boceprevir.

Bortezomib


The metabolism of Ruxolitinib can be decreased when combined with Bortezomib.

Bosentan


The serum concentration of Ruxolitinib can be decreased when it is combined with Bosentan.

Cabazitaxel


The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Ruxolitinib.

Calfactant


Ruxolitinib may increase the bradycardic activities of Calfactant.

Carbamazepine


The metabolism of Ruxolitinib can be increased when combined with Carbamazepine.

Carteolol


Ruxolitinib may increase the bradycardic activities of Carteolol.

Carvedilol


Ruxolitinib may increase the bradycardic activities of Carvedilol.

Ceritinib


The serum concentration of Ruxolitinib can be increased when it is combined with Ceritinib.

Clarithromycin


The serum concentration of Ruxolitinib can be increased when it is combined with Clarithromycin.

Clemastine


The metabolism of Ruxolitinib can be decreased when combined with Clemastine.

Clonidine


Ruxolitinib may increase the bradycardic activities of Clonidine.

Clotrimazole


The metabolism of Ruxolitinib can be decreased when combined with Clotrimazole.

Clozapine


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Clozapine.

Cobicistat


The serum concentration of Ruxolitinib can be increased when it is combined with Cobicistat.

Conivaptan


The serum concentration of Conivaptan can be increased when it is combined with Ruxolitinib.

Crizotinib


Ruxolitinib may increase the bradycardic activities of Crizotinib.

Cyclophosphamide


Cyclophosphamide may increase the cardiotoxic activities of Ruxolitinib.

Cyclophosphamide Anhydrous


Cyclophosphamide may increase the cardiotoxic activities of Ruxolitinib.

Cyclosporine


The metabolism of Ruxolitinib can be decreased when combined with Cyclosporine.

Dabrafenib


The serum concentration of Ruxolitinib can be decreased when it is combined with Dabrafenib.

Darunavir


The serum concentration of Ruxolitinib can be increased when it is combined with Darunavir.

Dasatinib


The serum concentration of Ruxolitinib can be increased when it is combined with Dasatinib.

Dasatinib Anhydrous


The serum concentration of Ruxolitinib can be increased when it is combined with Dasatinib.

Deferasirox


The serum concentration of Ruxolitinib can be decreased when it is combined with Deferasirox.

Delavirdine


The metabolism of Ruxolitinib can be decreased when combined with Delavirdine.

Denosumab


The risk or severity of adverse effects can be increased when Denosumab is combined with Ruxolitinib.

Deslanoside


Deslanoside may decrease the cardiotoxic activities of Ruxolitinib.

Dexmedetomidine


Ruxolitinib may increase the bradycardic activities of Dexmedetomidine.

Digitoxin


Digitoxin may decrease the cardiotoxic activities of Ruxolitinib.

Digoxin


Ruxolitinib may increase the bradycardic activities of Digoxin.

Dihydroergotamine


The metabolism of Ruxolitinib can be decreased when combined with Dihydroergotamine.

Diltiazem


Ruxolitinib may increase the bradycardic activities of Diltiazem.

Dipyrone


The risk or severity of myelosuppression can be increased when Metamizole is combined with Ruxolitinib.

Docetaxel


The risk or severity of adverse effects can be increased when Docetaxel is combined with Ruxolitinib.

DOCETAXEL ANHYDROUS


The risk or severity of adverse effects can be increased when Docetaxel is combined with Ruxolitinib.

Donepezil


Ruxolitinib may increase the bradycardic activities of Donepezil.

Doxycycline


The metabolism of Ruxolitinib can be decreased when combined with Doxycycline.

Doxycycline Anhydrous


The metabolism of Ruxolitinib can be decreased when combined with Doxycycline.

Dronedarone


Ruxolitinib may increase the bradycardic activities of Dronedarone.

Enzalutamide


The serum concentration of Ruxolitinib can be decreased when it is combined with Enzalutamide.

Erythromycin


The metabolism of Ruxolitinib can be decreased when combined with Erythromycin.

Esmolol


Ruxolitinib may increase the bradycardic activities of Esmolol.

Fingolimod


Ruxolitinib may increase the immunosuppressive activities of Fingolimod.

Fluconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Fluconazole.

Fluvoxamine


The metabolism of Ruxolitinib can be decreased when combined with Fluvoxamine.

Fosamprenavir


The metabolism of Ruxolitinib can be decreased when combined with Fosamprenavir.

Fosaprepitant


The serum concentration of Ruxolitinib can be increased when it is combined with Fosaprepitant.

Fosphenytoin


The metabolism of Ruxolitinib can be increased when combined with Fosphenytoin.

Fusidate


The serum concentration of Ruxolitinib can be increased when it is combined with Fusidic Acid.

Fusidic Acid


The serum concentration of Ruxolitinib can be increased when it is combined with Fusidic Acid.

Galantamine


Ruxolitinib may increase the bradycardic activities of Galantamine.

Guanfacine


Ruxolitinib may increase the bradycardic activities of Guanfacine.

Hepatitis A Vaccine, Inactivated


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Hepatitis A Vaccine.

Hepatitis B Surface Antigen Vaccine


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Hepatitis B Vaccine (Recombinant).

Hypoxis hemerocallidea root extract


The serum concentration of Ruxolitinib can be decreased when it is combined with St. John's Wort.

Idelalisib


The serum concentration of Ruxolitinib can be increased when it is combined with Idelalisib.

Imatinib


The metabolism of Ruxolitinib can be decreased when combined with Imatinib.

Indinavir


The serum concentration of Ruxolitinib can be increased when it is combined with Indinavir.

INDINAVIR ANHYDROUS


The serum concentration of Ruxolitinib can be increased when it is combined with Indinavir.

Isavuconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Isavuconazole.

Isavuconazonium


The metabolism of Ruxolitinib can be decreased when combined with Isavuconazonium.

Isradipine


The metabolism of Ruxolitinib can be decreased when combined with Isradipine.

Itraconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Itraconazole.

Ivabradine


Ruxolitinib may increase the bradycardic activities of Ivabradine.

Ivacaftor


The serum concentration of Ruxolitinib can be increased when it is combined with Ivacaftor.

Ketoconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Ketoconazole.

Labetalol


Ruxolitinib may increase the bradycardic activities of Labetalol.

Lanreotide


Ruxolitinib may increase the bradycardic activities of Lanreotide.

Leflunomide


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Leflunomide.

Levobunolol


Ruxolitinib may increase the bradycardic activities of Levobunolol.

Lopinavir


The serum concentration of Ruxolitinib can be increased when it is combined with Lopinavir.

Lovastatin


The metabolism of Ruxolitinib can be decreased when combined with Lovastatin.

Lucinactant


Ruxolitinib may increase the bradycardic activities of Lucinactant.

Luliconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Luliconazole.

Lumacaftor


The metabolism of Ruxolitinib can be increased when combined with Lumacaftor.

Methyldopa


Ruxolitinib may increase the bradycardic activities of Methyldopa.

METHYLDOPA ANHYDROUS


Ruxolitinib may increase the bradycardic activities of Methyldopa.

Metipranolol


Ruxolitinib may increase the bradycardic activities of Metipranolol.

Metoprolol


Ruxolitinib may increase the bradycardic activities of Metoprolol.

Mifepristone


The serum concentration of Ruxolitinib can be increased when it is combined with Mifepristone.

Mitotane


The serum concentration of Ruxolitinib can be decreased when it is combined with Mitotane.

Nadolol


Ruxolitinib may increase the bradycardic activities of Nadolol.

Natalizumab


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Natalizumab.

Nebivolol


Ruxolitinib may increase the bradycardic activities of Nebivolol.

Nefazodone


The serum concentration of Ruxolitinib can be increased when it is combined with Nefazodone.

Nelfinavir


The serum concentration of Ruxolitinib can be increased when it is combined with Nelfinavir.

Netupitant


The serum concentration of Ruxolitinib can be increased when it is combined with Netupitant.

Nevirapine


The metabolism of Ruxolitinib can be increased when combined with Nevirapine.

Nilotinib


The metabolism of Ruxolitinib can be decreased when combined with Nilotinib.

Ocrelizumab


Ocrelizumab may increase the immunosuppressive activities of Ruxolitinib.

Octreotide


Ruxolitinib may increase the bradycardic activities of Octreotide.

Olaparib


The metabolism of Ruxolitinib can be decreased when combined with Olaparib.

Osimertinib


The serum concentration of Ruxolitinib can be increased when it is combined with Osimertinib.

Ouabain


Ouabain may decrease the cardiotoxic activities of Ruxolitinib.

Ovine Digoxin Immune Fab


Digoxin Immune Fab (Ovine) may decrease the cardiotoxic activities of Ruxolitinib.

Paclitaxel


The risk or severity of adverse effects can be increased when Paclitaxel is combined with Ruxolitinib.

Palbociclib


The serum concentration of Ruxolitinib can be increased when it is combined with Palbociclib.

Pasireotide


Ruxolitinib may increase the bradycardic activities of Pasireotide.

Penbutolol


Ruxolitinib may increase the bradycardic activities of Penbutolol.

Pentobarbital


The metabolism of Ruxolitinib can be increased when combined with Pentobarbital.

Phenobarbital


The metabolism of Ruxolitinib can be increased when combined with Phenobarbital.

Phenytoin


The metabolism of Ruxolitinib can be increased when combined with Phenytoin.

Pimecrolimus


The risk or severity of adverse effects can be increased when Pimecrolimus is combined with Ruxolitinib.

Pindolol


Ruxolitinib may increase the bradycardic activities of Pindolol.

Poractant alfa


Ruxolitinib may increase the bradycardic activities of Poractant alfa.

Posaconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Posaconazole.

Primidone


The metabolism of Ruxolitinib can be increased when combined with Primidone.

Propafenone


Ruxolitinib may increase the bradycardic activities of Propafenone.

Propranolol


Ruxolitinib may increase the bradycardic activities of Propranolol.

Proscillaridin


Proscillaridin may decrease the cardiotoxic activities of Ruxolitinib.

Rabies Immune Globulin, Human


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Human rabies virus immune globulin.

Rabies Virus Vaccine Flury-Lep Strain


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Rabies virus inactivated antigen, A.

Ranolazine


The metabolism of Ruxolitinib can be decreased when combined with Ranolazine.

Rifabutin


The metabolism of Ruxolitinib can be increased when combined with Rifabutin.

Rifampin


The metabolism of Ruxolitinib can be increased when combined with Rifampicin.

Rifapentine


The metabolism of Ruxolitinib can be increased when combined with Rifapentine.

Rivastigmine


Ruxolitinib may increase the bradycardic activities of Rivastigmine.

Roflumilast


Roflumilast may increase the immunosuppressive activities of Ruxolitinib.

ROTAVIRUS VACCINE, LIVE


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Rotavirus Vaccine.

Rubella Virus Vaccine Live (wistar Ra 27-3 Strain)


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Rubella virus vaccine.

Rucaparib


The metabolism of Ruxolitinib can be decreased when combined with Rucaparib.

Salmonella enterica subsp. enterica serovar typhi


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Salmonella typhi ty21a live antigen.

Saquinavir


The serum concentration of Ruxolitinib can be increased when it is combined with Saquinavir.

Saquinavir Mesylate


The serum concentration of Ruxolitinib can be increased when it is combined with Saquinavir.

Sarilumab


The therapeutic efficacy of Ruxolitinib can be decreased when used in combination with Sarilumab.

Sildenafil


The metabolism of Ruxolitinib can be decreased when combined with Sildenafil.

Siltuximab


The serum concentration of Ruxolitinib can be decreased when it is combined with Siltuximab.

Simeprevir


The serum concentration of Ruxolitinib can be increased when it is combined with Simeprevir.

sipuleucel-T


The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Ruxolitinib.

Sotalol


Ruxolitinib may increase the bradycardic activities of Sotalol.

ST. JOHN'S WORT EXTRACT


The serum concentration of Ruxolitinib can be decreased when it is combined with St. John's Wort.

Sufentanil


Ruxolitinib may increase the bradycardic activities of Sufentanil.

Sulfisoxazole


The metabolism of Ruxolitinib can be decreased when combined with Sulfisoxazole.

Tacrolimus


Tacrolimus may increase the immunosuppressive activities of Ruxolitinib.

Telaprevir


The serum concentration of Ruxolitinib can be increased when it is combined with Telaprevir.

Telithromycin


The serum concentration of Ruxolitinib can be increased when it is combined with Telithromycin.

Tetanus Toxoid Vaccine, Inactivated


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Clostridium tetani toxoid antigen (formaldehyde inactivated).

Ticlopidine


The metabolism of Ruxolitinib can be decreased when combined with Ticlopidine.

Timolol


Ruxolitinib may increase the bradycardic activities of Timolol.

Timolol Anhydrous


Ruxolitinib may increase the bradycardic activities of Timolol.

Tizanidine


Ruxolitinib may increase the bradycardic activities of Tizanidine.

Tocilizumab


The serum concentration of Ruxolitinib can be decreased when it is combined with Tocilizumab.

Tofacitinib


Ruxolitinib may increase the immunosuppressive activities of Tofacitinib.

Trastuzumab


Trastuzumab may increase the cardiotoxic activities of Ruxolitinib.

Typhoid Vaccine Live Ty21a


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Salmonella typhi ty21a live antigen.

Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Salmonella typhi ty2 vi polysaccharide antigen.

Varicella Virus Vaccine Live (Oka-Merck) strain


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Varicella Zoster Vaccine (Live/Attenuated).

Vemurafenib


The serum concentration of Ruxolitinib can be decreased when it is combined with Vemurafenib.

Venlafaxine


The metabolism of Ruxolitinib can be decreased when combined with Venlafaxine.

Verapamil


Ruxolitinib may increase the bradycardic activities of Verapamil.

Voriconazole


The serum concentration of Ruxolitinib can be increased when it is combined with Voriconazole.

Yellow Fever Vaccine


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Yellow Fever Vaccine.

Yellow-Fever Virus Vaccine, 17D-204 strain


The risk or severity of adverse effects can be increased when Ruxolitinib is combined with Yellow Fever Vaccine.

Ziprasidone


The metabolism of Ruxolitinib can be decreased when combined with Ziprasidone.

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