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Trabectedin Interaction with other Drugs


Trabectedin is an anticancer medicine prescribed to treat advanced soft tissue sarcoma such as liposarcoma, a cancer of fat cells and leiomyosarcoma, a cancer of smooth muscle tissue.

Trabectedin Interaction with 224 drugs. Find out more in the list below:

Abiraterone


The serum concentration of Trabectedin can be increased when it is combined with Abiraterone.

Acetyldigitoxin


Acetyldigitoxin may decrease the cardiotoxic activities of Trabectedin.

Amiodarone


The serum concentration of Trabectedin can be increased when it is combined with Amiodarone.

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Ancestim


The risk or severity of cytotoxicity can be increased when Ancestim is combined with Trabectedin.

Anhydrous Tacrolimus


Tacrolimus may increase the immunosuppressive activities of Trabectedin.

Anthrax immune globulin, human


The risk or severity of adverse effects can be increased when Trabectedin is combined with Anthrax immune globulin human.

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Apalutamide


The serum concentration of Trabectedin can be decreased when it is combined with Apalutamide.

Aprepitant


The serum concentration of Trabectedin can be increased when it is combined with Aprepitant.

Armodafinil


The metabolism of Trabectedin can be decreased when combined with Armodafinil.

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Artemether


The metabolism of Trabectedin can be decreased when combined with Artemether.

Atazanavir


The serum concentration of Trabectedin can be increased when it is combined with Atazanavir.

Atomoxetine


The metabolism of Trabectedin can be decreased when combined with Atomoxetine.

Atorvastatin


Atorvastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

BCG Vaccine


The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Trabectedin.

BCG, Live, Connaught Strain


The risk or severity of adverse effects can be increased when Trabectedin is combined with Bacillus calmette-guerin substrain connaught live antigen.

BCG, Live, Tice Strain


The risk or severity of adverse effects can be increased when Trabectedin is combined with Bacillus calmette-guerin substrain tice live antigen.

Betaxolol


The metabolism of Trabectedin can be decreased when combined with Betaxolol.

Bevacizumab


Bevacizumab may increase the cardiotoxic activities of Trabectedin.

Bevacizumab-Awwb


Bevacizumab may increase the cardiotoxic activities of Trabectedin.

Boceprevir


The serum concentration of Trabectedin can be increased when it is combined with Boceprevir.

Bortezomib


The metabolism of Trabectedin can be decreased when combined with Bortezomib.

Bosentan


The serum concentration of Trabectedin can be decreased when it is combined with Bosentan.

Bupropion


The metabolism of Trabectedin can be decreased when combined with Bupropion.

Cabazitaxel


The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Trabectedin.

Capecitabine


The metabolism of Trabectedin can be decreased when combined with Capecitabine.

Carbamazepine


The serum concentration of Trabectedin can be decreased when it is combined with Carbamazepine.

Celecoxib


The metabolism of Trabectedin can be decreased when combined with Celecoxib.

Ceritinib


The serum concentration of Trabectedin can be increased when it is combined with Ceritinib.

Cerivastatin


Cerivastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

Chloramphenicol


The metabolism of Trabectedin can be decreased when combined with Chloramphenicol.

Chloroquine


The metabolism of Trabectedin can be decreased when combined with Chloroquine.

Chlorpromazine


The metabolism of Trabectedin can be decreased when combined with Chlorpromazine.

Cholecalciferol


The metabolism of Trabectedin can be decreased when combined with Cholecalciferol.

Cimetidine


The metabolism of Trabectedin can be decreased when combined with Cimetidine.

Cinacalcet


The metabolism of Trabectedin can be decreased when combined with Cinacalcet.

Citalopram


The metabolism of Trabectedin can be decreased when combined with Citalopram.

Clarithromycin


The serum concentration of Trabectedin can be increased when it is combined with Clarithromycin.

Clemastine


The metabolism of Trabectedin can be decreased when combined with Clemastine.

Clobazam


The metabolism of Trabectedin can be decreased when combined with Clobazam.

Clomipramine


The metabolism of Trabectedin can be decreased when combined with Clomipramine.

Clotrimazole


The metabolism of Trabectedin can be decreased when combined with Clotrimazole.

Clozapine


The risk or severity of adverse effects can be increased when Trabectedin is combined with Clozapine.

Cobicistat


The serum concentration of Trabectedin can be increased when it is combined with Cobicistat.

Cocaine


The metabolism of Trabectedin can be decreased when combined with Cocaine.

Conivaptan


The serum concentration of Conivaptan can be increased when it is combined with Trabectedin.

Crisaborole


The metabolism of Trabectedin can be decreased when combined with Crisaborole.

Crizotinib


The metabolism of Trabectedin can be decreased when combined with Crizotinib.

Cyclophosphamide


Cyclophosphamide may increase the cardiotoxic activities of Trabectedin.

Cyclophosphamide Anhydrous


Cyclophosphamide may increase the cardiotoxic activities of Trabectedin.

Cyclosporine


The metabolism of Trabectedin can be decreased when combined with Cyclosporine.

Cyproterone Acetate


The serum concentration of Trabectedin can be decreased when it is combined with Cyproterone acetate.

Dabrafenib


The serum concentration of Trabectedin can be decreased when it is combined with Dabrafenib.

Darifenacin


The metabolism of Trabectedin can be decreased when combined with Darifenacin.

Darunavir


The serum concentration of Trabectedin can be increased when it is combined with Darunavir.

Dasatinib


The serum concentration of Trabectedin can be increased when it is combined with Dasatinib.

Dasatinib Anhydrous


The serum concentration of Trabectedin can be increased when it is combined with Dasatinib.

Deferasirox


The serum concentration of Trabectedin can be decreased when it is combined with Deferasirox.

Delavirdine


The metabolism of Trabectedin can be decreased when combined with Delavirdine.

Denosumab


The risk or severity of adverse effects can be increased when Denosumab is combined with Trabectedin.

Desipramine


The metabolism of Trabectedin can be decreased when combined with Desipramine.

Deslanoside


Deslanoside may decrease the cardiotoxic activities of Trabectedin.

Digitoxin


Digitoxin may decrease the cardiotoxic activities of Trabectedin.

Digoxin


Digoxin may decrease the cardiotoxic activities of Trabectedin.

Dihydroergotamine


The metabolism of Trabectedin can be decreased when combined with Dihydroergotamine.

Diltiazem


The metabolism of Trabectedin can be decreased when combined with Diltiazem.

Diphenhydramine


The metabolism of Trabectedin can be decreased when combined with Diphenhydramine.

Dipyrone


The risk or severity of myelosuppression can be increased when Metamizole is combined with Trabectedin.

Docetaxel


The risk or severity of adverse effects can be increased when Docetaxel is combined with Trabectedin.

DOCETAXEL ANHYDROUS


The risk or severity of adverse effects can be increased when Docetaxel is combined with Trabectedin.

Dothiepin


The metabolism of Trabectedin can be decreased when combined with Dosulepin.

Doxycycline


The metabolism of Trabectedin can be decreased when combined with Doxycycline.

Doxycycline Anhydrous


The metabolism of Trabectedin can be decreased when combined with Doxycycline.

Dronedarone


The metabolism of Trabectedin can be decreased when combined with Dronedarone.

Duloxetine


The metabolism of Trabectedin can be decreased when combined with Duloxetine.

Efavirenz


The metabolism of Trabectedin can be decreased when combined with Efavirenz.

Eliglustat


The metabolism of Trabectedin can be decreased when combined with Eliglustat.

Enzalutamide


The serum concentration of Trabectedin can be decreased when it is combined with Enzalutamide.

Erythromycin


The metabolism of Trabectedin can be decreased when combined with Erythromycin.

Eslicarbazepine Acetate


The metabolism of Trabectedin can be decreased when combined with Eslicarbazepine acetate.

Esomeprazole


The metabolism of Trabectedin can be decreased when combined with Esomeprazole.

Ethanol


Ethanol may increase the hepatotoxic activities of Trabectedin.

Etravirine


The metabolism of Trabectedin can be decreased when combined with Etravirine.

Fingolimod


Trabectedin may increase the immunosuppressive activities of Fingolimod.

Floxuridine


The metabolism of Trabectedin can be decreased when combined with Floxuridine.

Fluconazole


The metabolism of Trabectedin can be decreased when combined with Fluconazole.

Fluorouracil


The metabolism of Trabectedin can be decreased when combined with Fluorouracil.

Fluoxetine


The metabolism of Trabectedin can be decreased when combined with Fluoxetine.

Fluvastatin


Fluvastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

Fluvoxamine


The metabolism of Trabectedin can be decreased when combined with Fluvoxamine.

Fosamprenavir


The metabolism of Trabectedin can be decreased when combined with Fosamprenavir.

Fosaprepitant


The serum concentration of Trabectedin can be increased when it is combined with Fosaprepitant.

Fosphenytoin


The serum concentration of Trabectedin can be decreased when it is combined with Fosphenytoin.

Fusidate


The serum concentration of Trabectedin can be increased when it is combined with Fusidic Acid.

Fusidic Acid


The serum concentration of Trabectedin can be increased when it is combined with Fusidic Acid.

Gemfibrozil


The metabolism of Trabectedin can be decreased when combined with Gemfibrozil.

Haloperidol


The metabolism of Trabectedin can be decreased when combined with Haloperidol.

Hepatitis A Vaccine, Inactivated


The risk or severity of adverse effects can be increased when Trabectedin is combined with Hepatitis A Vaccine.

Hepatitis B Surface Antigen Vaccine


The risk or severity of adverse effects can be increased when Trabectedin is combined with Hepatitis B Vaccine (Recombinant).

Hypoxis hemerocallidea root extract


The serum concentration of Trabectedin can be decreased when it is combined with St. John's Wort.

Idelalisib


The serum concentration of Trabectedin can be increased when it is combined with Idelalisib.

Imatinib


The metabolism of Trabectedin can be decreased when combined with Imatinib.

Imipramine


The metabolism of Trabectedin can be decreased when combined with Imipramine.

Indinavir


The serum concentration of Trabectedin can be increased when it is combined with Indinavir.

INDINAVIR ANHYDROUS


The serum concentration of Trabectedin can be increased when it is combined with Indinavir.

Irbesartan


The metabolism of Trabectedin can be decreased when combined with Irbesartan.

Isavuconazole


The serum concentration of Trabectedin can be increased when it is combined with Isavuconazole.

Isavuconazonium


The metabolism of Trabectedin can be decreased when combined with Isavuconazonium.

Isoniazid


The metabolism of Trabectedin can be decreased when combined with Isoniazid.

Isradipine


The metabolism of Trabectedin can be decreased when combined with Isradipine.

Itraconazole


The serum concentration of Trabectedin can be increased when it is combined with Itraconazole.

Ivacaftor


The serum concentration of Trabectedin can be increased when it is combined with Ivacaftor.

Ketoconazole


The serum concentration of Trabectedin can be increased when it is combined with Ketoconazole.

Leflunomide


The risk or severity of adverse effects can be increased when Trabectedin is combined with Leflunomide.

Lopinavir


The serum concentration of Trabectedin can be increased when it is combined with Lopinavir.

Lorcaserin


The metabolism of Trabectedin can be decreased when combined with Lorcaserin.

Losartan


The metabolism of Trabectedin can be decreased when combined with Losartan.

Lovastatin


Lovastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

Luliconazole


The serum concentration of Trabectedin can be increased when it is combined with Luliconazole.

Lumacaftor


The serum concentration of Trabectedin can be decreased when it is combined with Lumacaftor.

Lumefantrine


The metabolism of Trabectedin can be decreased when combined with Lumefantrine.

Manidipine


The metabolism of Trabectedin can be decreased when combined with Manidipine.

Methadone


The metabolism of Trabectedin can be decreased when combined with Methadone.

Methotrimeprazine


The metabolism of Trabectedin can be decreased when combined with Methotrimeprazine.

Metoprolol


The metabolism of Trabectedin can be decreased when combined with Metoprolol.

Midostaurin


The serum concentration of Trabectedin can be increased when it is combined with Midostaurin.

Mifepristone


The serum concentration of Trabectedin can be increased when it is combined with Mifepristone.

Mirabegron


The metabolism of Trabectedin can be decreased when combined with Mirabegron.

Mitotane


The serum concentration of Trabectedin can be decreased when it is combined with Mitotane.

Moclobemide


The metabolism of Trabectedin can be decreased when combined with Moclobemide.

Modafinil


The metabolism of Trabectedin can be decreased when combined with Modafinil.

Natalizumab


The risk or severity of adverse effects can be increased when Trabectedin is combined with Natalizumab.

Nefazodone


The serum concentration of Trabectedin can be increased when it is combined with Nefazodone.

Nelfinavir


The serum concentration of Trabectedin can be increased when it is combined with Nelfinavir.

Netupitant


The serum concentration of Trabectedin can be increased when it is combined with Netupitant.

Nevirapine


The serum concentration of Trabectedin can be decreased when it is combined with Nevirapine.

Nicardipine


The metabolism of Trabectedin can be decreased when combined with Nicardipine.

Nicotine


The metabolism of Trabectedin can be decreased when combined with Nicotine.

Nicotine Polacrilex


The metabolism of Trabectedin can be decreased when combined with Nicotine.

Nilotinib


The metabolism of Trabectedin can be decreased when combined with Nilotinib.

Ocrelizumab


Ocrelizumab may increase the immunosuppressive activities of Trabectedin.

Olaparib


The metabolism of Trabectedin can be decreased when combined with Olaparib.

Omeprazole


The metabolism of Trabectedin can be decreased when combined with Omeprazole.

Osimertinib


The serum concentration of Trabectedin can be increased when it is combined with Osimertinib.

Ouabain


Ouabain may decrease the cardiotoxic activities of Trabectedin.

Ovine Digoxin Immune Fab


Digoxin Immune Fab (Ovine) may decrease the cardiotoxic activities of Trabectedin.

Paclitaxel


The risk or severity of adverse effects can be increased when Paclitaxel is combined with Trabectedin.

Palbociclib


The serum concentration of Trabectedin can be increased when it is combined with Palbociclib.

Panobinostat


The serum concentration of Trabectedin can be increased when it is combined with Panobinostat.

Pantoprazole


The metabolism of Trabectedin can be decreased when combined with Pantoprazole.

Paroxetine


The metabolism of Trabectedin can be decreased when combined with Paroxetine.

Peginterferon Alfa-2b


The serum concentration of Trabectedin can be decreased when it is combined with Peginterferon alfa-2b.

Pentobarbital


The serum concentration of Trabectedin can be decreased when it is combined with Pentobarbital.

Phenobarbital


The serum concentration of Trabectedin can be decreased when it is combined with Phenobarbital.

Phenytoin


The serum concentration of Trabectedin can be decreased when it is combined with Phenytoin.

Pimecrolimus


The risk or severity of adverse effects can be increased when Pimecrolimus is combined with Trabectedin.

Pitavastatin


Pitavastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

Posaconazole


The serum concentration of Trabectedin can be increased when it is combined with Posaconazole.

Pravastatin


Pravastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

Primidone


The serum concentration of Trabectedin can be decreased when it is combined with Primidone.

Promazine


The metabolism of Trabectedin can be decreased when combined with Promazine.

Proscillaridin


Proscillaridin may decrease the cardiotoxic activities of Trabectedin.

Pyrimethamine


The metabolism of Trabectedin can be decreased when combined with Pyrimethamine.

Quinidine


The metabolism of Trabectedin can be decreased when combined with Quinidine.

Quinine


The metabolism of Trabectedin can be decreased when combined with Quinine.

Rabies Immune Globulin, Human


The risk or severity of adverse effects can be increased when Trabectedin is combined with Human rabies virus immune globulin.

Rabies Virus Vaccine Flury-Lep Strain


The risk or severity of adverse effects can be increased when Trabectedin is combined with Rabies virus inactivated antigen, A.

Ranolazine


The metabolism of Trabectedin can be decreased when combined with Ranolazine.

Rifabutin


The serum concentration of Trabectedin can be decreased when it is combined with Rifabutin.

Rifampin


The serum concentration of Trabectedin can be decreased when it is combined with Rifampicin.

Rifapentine


The serum concentration of Trabectedin can be decreased when it is combined with Rifapentine.

Ritonavir


The metabolism of Trabectedin can be decreased when combined with Ritonavir.

Roflumilast


Roflumilast may increase the immunosuppressive activities of Trabectedin.

Rolapitant


The metabolism of Trabectedin can be decreased when combined with Rolapitant.

Ropinirole


The metabolism of Trabectedin can be decreased when combined with Ropinirole.

Rosuvastatin


Rosuvastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

ROTAVIRUS VACCINE, LIVE


The risk or severity of adverse effects can be increased when Trabectedin is combined with Rotavirus Vaccine.

Rubella Virus Vaccine Live (wistar Ra 27-3 Strain)


The risk or severity of adverse effects can be increased when Trabectedin is combined with Rubella virus vaccine.

Rucaparib


The metabolism of Trabectedin can be decreased when combined with Rucaparib.

Salmonella enterica subsp. enterica serovar typhi


The risk or severity of adverse effects can be increased when Trabectedin is combined with Salmonella typhi ty21a live antigen.

Saquinavir


The serum concentration of Trabectedin can be increased when it is combined with Saquinavir.

Saquinavir Mesylate


The serum concentration of Trabectedin can be increased when it is combined with Saquinavir.

Sarilumab


The therapeutic efficacy of Trabectedin can be decreased when used in combination with Sarilumab.

Secobarbital


The metabolism of Trabectedin can be increased when combined with Secobarbital.

Sertraline


The metabolism of Trabectedin can be decreased when combined with Sertraline.

Sildenafil


The metabolism of Trabectedin can be decreased when combined with Sildenafil.

Siltuximab


The serum concentration of Trabectedin can be decreased when it is combined with Siltuximab.

Simeprevir


The serum concentration of Trabectedin can be increased when it is combined with Simeprevir.

Simvastatin


Simvastatin may increase the myopathic rhabdomyolysis activities of Trabectedin.

sipuleucel-T


The therapeutic efficacy of Sipuleucel-T can be decreased when used in combination with Trabectedin.

Sorafenib


The metabolism of Trabectedin can be decreased when combined with Sorafenib.

ST. JOHN'S WORT EXTRACT


The serum concentration of Trabectedin can be decreased when it is combined with St. John's Wort.

Sulfadiazine


The metabolism of Trabectedin can be decreased when combined with Sulfadiazine.

Sulfamethoxazole


The metabolism of Trabectedin can be decreased when combined with Sulfamethoxazole.

Sulfisoxazole


The metabolism of Trabectedin can be decreased when combined with Sulfisoxazole.

Tacrolimus


Tacrolimus may increase the immunosuppressive activities of Trabectedin.

Telaprevir


The serum concentration of Trabectedin can be increased when it is combined with Telaprevir.

Telithromycin


The serum concentration of Trabectedin can be increased when it is combined with Telithromycin.

Terbinafine


The metabolism of Trabectedin can be decreased when combined with Terbinafine.

Tetanus Toxoid Vaccine, Inactivated


The risk or severity of adverse effects can be increased when Trabectedin is combined with Clostridium tetani toxoid antigen (formaldehyde inactivated).

Thioridazine


The metabolism of Trabectedin can be decreased when combined with Thioridazine.

Ticagrelor


The metabolism of Trabectedin can be decreased when combined with Ticagrelor.

Ticlopidine


The metabolism of Trabectedin can be decreased when combined with Ticlopidine.

Tipranavir


The metabolism of Trabectedin can be decreased when combined with Tipranavir.

Tocilizumab


The serum concentration of Trabectedin can be decreased when it is combined with Tocilizumab.

Tofacitinib


Trabectedin may increase the immunosuppressive activities of Tofacitinib.

Tolbutamide


The metabolism of Trabectedin can be decreased when combined with Tolbutamide.

Topiramate


The metabolism of Trabectedin can be decreased when combined with Topiramate.

Tranylcypromine


The metabolism of Trabectedin can be decreased when combined with Tranylcypromine.

Trastuzumab


Trastuzumab may increase the cardiotoxic activities of Trabectedin.

Trimethoprim


The metabolism of Trabectedin can be decreased when combined with Trimethoprim.

Typhoid Vaccine Live Ty21a


The risk or severity of adverse effects can be increased when Trabectedin is combined with Salmonella typhi ty21a live antigen.

Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain


The risk or severity of adverse effects can be increased when Trabectedin is combined with Salmonella typhi ty2 vi polysaccharide antigen.

Valproate


The metabolism of Trabectedin can be decreased when combined with Valproic Acid.

Valproic Acid


The metabolism of Trabectedin can be decreased when combined with Valproic Acid.

Valsartan


The metabolism of Trabectedin can be decreased when combined with Valsartan.

Varicella Virus Vaccine Live (Oka-Merck) strain


The risk or severity of adverse effects can be increased when Trabectedin is combined with Varicella Zoster Vaccine (Live/Attenuated).

Vemurafenib


The serum concentration of Trabectedin can be decreased when it is combined with Vemurafenib.

Venlafaxine


The metabolism of Trabectedin can be decreased when combined with Venlafaxine.

Verapamil


The metabolism of Trabectedin can be decreased when combined with Verapamil.

Voriconazole


The serum concentration of Trabectedin can be increased when it is combined with Voriconazole.

Yellow Fever Vaccine


The risk or severity of adverse effects can be increased when Trabectedin is combined with Yellow Fever Vaccine.

Yellow-Fever Virus Vaccine, 17D-204 strain


The risk or severity of adverse effects can be increased when Trabectedin is combined with Yellow Fever Vaccine.

Zafirlukast


The metabolism of Trabectedin can be decreased when combined with Zafirlukast.

Ziprasidone


The metabolism of Trabectedin can be decreased when combined with Ziprasidone.

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