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How to Take Ampicillin and Sulbactam and it's Dose


It comes as a solution for injection, to be administered by a healthcare provider into the large muscle or the vein. It also comes as a tablet for oral use.

Dosage & When it is to be taken

Dose is based on ampicillin dose. IV Endocarditis 2g 6 hourly for 4-6 week with gentamicin or vancomycin. Aspiration, community-acquired pneumonia 1-2g 6 hourly. Hospital-acquired pneumonia 2g 6 hourly. IV/IM Susceptible infections 1-2g 6 hrly. Max: 8 g/day. Uncomplicated gonorrhoea 1-2g as single dose, may use with oral probenecid. Acute pelvic inflammatory disease 2g 6 hourly with IV or oral doxycycline. Discontinue parenteral treatment 24 hr after clinical improvement; continue oral doxycycline to complete 14 days of treatment. The total dose of sulbactam should not exceed 4gms per day.
Pediatric Patients 1 year of age or older recommended dosage is 300 mg per kg of body weight administered via IV infusion in equally divided doses every 6 hours.

When it is not to be taken (Contraindications)

Allergic to penicillins, infectious mononucleosis (kissing disease).

Drug Name : Ampicillin and Sulbactam

This medication is a penicillin antibiotic, prescribed for susceptible bacterial infections like skin infections, gynecological infections or infections of the abdomen either alone or with other medications.


Trade Names/Brand Names of Ampicillin and Sulbactam

India :


International :


Unasyn, Subacillin, Sultamicillin
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