• Avatrombopag tablets are available at a strength of 20 mg and should be taken by mouth once a day with food to avoid gastric discomfort.
• Do not take for more than 5 days unless otherwise recommended by the physician.
Platelet count (×109/L) and the recommended dose:
• Count 50 to 40 × 109/L: Take 40 mg (2 tablets) of avatrombopag once a day for five consecutive days
• Count below 40 × 109/L: Take 60 mg (3 tablets) of avatrombopag once daily for five consecutive days
• Allergy to avatrombopag
• Pregnancy and breastfeeding
• Children below 18 years of age
• History of clotting disorders (e.g., Thrombophilia)
• Severely dehydrated patients (e.g., Hyponatremia or abnormally low sodium level)
Caution is required in treating the following patients as safety and effectiveness parameters have not been studied in these groups
• Severe kidney disease or in patients undergoing hemodialysis
• Geriatric cases
• Do not take for more than 5 days unless otherwise recommended by the physician.
Dosage & When it is to be taken
The recommended adult dose of avatrombopag depends on the individual patient’s platelet count performed before a procedure is planned.Platelet count (×109/L) and the recommended dose:
• Count 50 to 40 × 109/L: Take 40 mg (2 tablets) of avatrombopag once a day for five consecutive days
• Count below 40 × 109/L: Take 60 mg (3 tablets) of avatrombopag once daily for five consecutive days
When it is not to be taken (Contraindications)
Avatrombopag should not be used with a focus to normalize platelet counts and in patients with-• Allergy to avatrombopag
• Pregnancy and breastfeeding
• Children below 18 years of age
• History of clotting disorders (e.g., Thrombophilia)
• Severely dehydrated patients (e.g., Hyponatremia or abnormally low sodium level)
Caution is required in treating the following patients as safety and effectiveness parameters have not been studied in these groups
• Severe kidney disease or in patients undergoing hemodialysis
• Geriatric cases
