Dacomitinib is available in tablet form which should be taken by mouth one time daily either with or without food.
Take the dacomitinib tablets at the same time every day exactly as directed by the doctor.
Do not break, split or chew the tablet but swallow as a whole with sufficient quantity of water.
Never stop taking dacomitinib tablets unless otherwise suggested by your doctor.
The dose of dacomitinib can be reduced or adjusted to 30 mg if any severe side effects occur.
The dose can further be reduced to 15 mg once daily but discontinue dacomitinib treatment if there is a need for further dose reduction.
The treatment with dacomitinib can be continued until the progression of the disease or until the treatment with the drug does not result in intolerable toxicity.
• If there is an allergy to dacomitinib
• Pregnant and breastfeeding mothers
• Interstitial lung disease (Lung stiffness causing breathing difficulty)
• Children - Due to lack of safety and effectiveness data in these age groups
Extreme caution is required while treating patients with severe liver or kidney damage.
Take the next dose as per your following schedule. Do not take a double dose to make up for the missed dose of dacomitinib which can be very harmful.
Take the dacomitinib tablets at the same time every day exactly as directed by the doctor.
Do not break, split or chew the tablet but swallow as a whole with sufficient quantity of water.
Never stop taking dacomitinib tablets unless otherwise suggested by your doctor.
Dosage & When it is to be taken
The recommended adult dose of dacomitinib is 45 mg once daily.The dose of dacomitinib can be reduced or adjusted to 30 mg if any severe side effects occur.
The dose can further be reduced to 15 mg once daily but discontinue dacomitinib treatment if there is a need for further dose reduction.
The treatment with dacomitinib can be continued until the progression of the disease or until the treatment with the drug does not result in intolerable toxicity.
When it is not to be taken (Contraindications)
Dacomitinib should not be used in patients-• If there is an allergy to dacomitinib
• Pregnant and breastfeeding mothers
• Interstitial lung disease (Lung stiffness causing breathing difficulty)
• Children - Due to lack of safety and effectiveness data in these age groups
Extreme caution is required while treating patients with severe liver or kidney damage.
What if you Miss a Dose of Dacomitinib?
If a patient forgets to take a dose or vomits after taking dacomitinib tablets, do not take an additional dose.Take the next dose as per your following schedule. Do not take a double dose to make up for the missed dose of dacomitinib which can be very harmful.
