• Duvelisib comes as a capsule and should be taken by mouth either with or without food.
• Swallow the duvelisib capsule as a whole with a sufficient quantity of water.
• Do not chew, break, or open the capsule.
• Take the capsules exactly at the same time every day.
• Patients should be treated with certain antiviral medications with the intention to prevent cytomegalovirus (CMV) infections and reactivation of CMV.
• Preventive measures must be followed during treatment with duvelisib to avoid Pneumocystis jiroveci pneumonia (PJP). If PJP is suspected, duvelisib therapy has to be stopped immediately.
• The dose of duvelisib can be reduced or adjusted to 15 mg twice daily if any severe side effects occur.
• Discontinue the treatment with duvelisib permanently if the patient is unable to tolerate the reduced dose (15 mg twice daily).
• If there is an allergy to duvelisib
• Pregnant and breastfeeding women
• Children
• Never take the missed dose, if the time has exceeded 6 hours. Take the following dose as per the next scheduled time.
• Do not take an extra dose of duvelisib to make up for the missed dose as it can result in harm to the patients.
• Swallow the duvelisib capsule as a whole with a sufficient quantity of water.
• Do not chew, break, or open the capsule.
• Take the capsules exactly at the same time every day.
Dosage & When it is to be taken
• The recommended dose of duvelisib is 25 mg twice daily taken continuously in 28-days treatment cycles.• Patients should be treated with certain antiviral medications with the intention to prevent cytomegalovirus (CMV) infections and reactivation of CMV.
• Preventive measures must be followed during treatment with duvelisib to avoid Pneumocystis jiroveci pneumonia (PJP). If PJP is suspected, duvelisib therapy has to be stopped immediately.
• The dose of duvelisib can be reduced or adjusted to 15 mg twice daily if any severe side effects occur.
• Discontinue the treatment with duvelisib permanently if the patient is unable to tolerate the reduced dose (15 mg twice daily).
When it is not to be taken (Contraindications)
Duvelisib should not be used in patients-• If there is an allergy to duvelisib
• Pregnant and breastfeeding women
• Children
What if you Miss a Dose of Duvelisib?
• If the dose of duvelisib missed is within 6 hours take it as soon as possible.• Never take the missed dose, if the time has exceeded 6 hours. Take the following dose as per the next scheduled time.
• Do not take an extra dose of duvelisib to make up for the missed dose as it can result in harm to the patients.
