• Moxonidine comes as a tablet which should be taken by mouth.
• It can be taken either before or after food as moxonidine has no interaction with food.
• The tablet should be swallowed whole with sufficient quantity of water.
• If the therapeutic effect is insufficient, the dosage can be increased to 400 mcg per day after three weeks either as a single dose in the morning or twice daily in the morning and evening.
• The dosage can further be increased to 600 mcg two times daily if effects are still not seen. However, the maximum dosage should not exceed 600 mcg in a day 400 mcg for a single dose.
• Allergy to moxonidine drug
• Rare hereditary problems such as galactose intolerance, malabsorption of glucose and galactose or Lapp lactase deficiency
• History of angioedema
• Severe heart failure
• Heart conduction disorders such as sick sinus syndrome and sino-atrial block
• Raynaud’s syndrome (arterial spasm which results in reduced blood flow)
• Severe liver or kidney disease
• Depression and seizure disorders
• Intermittent claudication
• It can be taken either before or after food as moxonidine has no interaction with food.
• The tablet should be swallowed whole with sufficient quantity of water.
Dosage & When it is to be taken
• The recommended adult dosage of moxonidine is 200 micrograms (mcg) daily.• If the therapeutic effect is insufficient, the dosage can be increased to 400 mcg per day after three weeks either as a single dose in the morning or twice daily in the morning and evening.
• The dosage can further be increased to 600 mcg two times daily if effects are still not seen. However, the maximum dosage should not exceed 600 mcg in a day 400 mcg for a single dose.
When it is not to be taken (Contraindications)
Moxonidine should not be used in patients with:• Allergy to moxonidine drug
• Rare hereditary problems such as galactose intolerance, malabsorption of glucose and galactose or Lapp lactase deficiency
• History of angioedema
• Severe heart failure
• Heart conduction disorders such as sick sinus syndrome and sino-atrial block
• Raynaud’s syndrome (arterial spasm which results in reduced blood flow)
• Severe liver or kidney disease
• Depression and seizure disorders
• Intermittent claudication