How to Take Panobinostat and it's Dose

Last Updated on Nov 08, 2024

Panobinostat Capsules are taken by mouth (orally) in doses 10 mg, 15 mg, or 20 mg.
Patients are advised not to change the prescribed dose or stop taking the capsules suddenly.

Dosage & When it is to be taken

The recommended initial dose is 20 mg, taken by mouth once every alternate day for 3 doses per week. Continue this for every 1st 2 weeks of a 21-day cycle for up to 8 cycles.
Continue treatment for an additional 8 cycles in patients who do not experience severe side effects.
The total duration of treatment that can be given is up to 16 cycles or for 48 weeks.
It is given along with bortezomib and dexamethasone. Bortezomib is given as 1.3 mg/m² injection and dexamethasone is given as 20 mg tablet on a full stomach.

When it is not to be taken (Contraindications)

It should not be used in patients who are having allergy to panobinostat.

What if you Miss a Dose of Panobinostat?

If a panobinostat capsule is missed, it can be taken till 12 hours after the specified dose time. The patient should not repeat the dose if vomiting occurs but, should take the next dose as scheduled.