How to Take Sibutramine and it's Dose

Last Updated on Nov 08, 2024

• Sibutramine comes as a capsule or tablet to be taken by mouth. It can be taken either with or without food and should be taken in the morning.
• Sibutramine should not be used for more than two years.

Dosage & When it is to be taken

• The initial recommended dosage for adults is 10mg once daily.
• The dosage can be increased to 15mg once a day (only after 4 weeks) particularly in those who do not show a positive response to a low-calorie diet and exercise.
• The dose of 5mg is used in patients who do not tolerate with a usual 10mg dose.

When it is not to be taken (Contraindications)

Sibutramine should not be used in patients with the following conditions:

• Allergy to the drug
• Congestive heart failure, serious abnormal heart rhythms, chest pain, episodes of heart attack and stroke
• Major eating disorder (anorexia nervosa or bulimia nervosa)
• Uncontrolled hypertension
• Overactive thyroid
• History of depressive or maniac illness
• Seizure disorders
• Closed angle glaucoma ( increased pressure in the eye resulting in optic nerve damage)
• Pheochromocytoma (tumor in the adrenal medulla)
• Severe liver damage or kidney damage particularly in patients on dialysis
• Along with medications like monoamine oxide inhibitors I (MAO I) or other centrally acting weight loss drugs

Drug Name : Sibutramine

Sibutramine has been banned in several countries including the United States, European countries and India due to its cardiovascular side effects like heart attack and stroke.