Mix each packet of uridine granules with 4 ounces or 100 ml of soft food such as applesauce, pudding or yogurt in a small container.
Crush the contents of one full 10-gram packet of granules to a fine powder. Add the crushed granules to 4 ounces (100 mL) of the starch-based thickening product.
Prepare the mixture at a ratio of no greater than 1 gram per 10 mL of reconstituted food while giving to pediatric patients receiving less than 10 grams.
Take this within 30 minutes of mixing.
At least 4 ounces of water should be taken to make sure that patient swallow all of the medicine.
In children, the dose should be given based on their weight.
In case of vomiting, take another full dose as soon as possible and then the next dose at a regular scheduled time.
The dose should be measured using either a scale accurate to at least 0.1 gram, or a graduated teaspoon accurate to ¼ teaspoon.
Administer full course which is 20 doses as directed by the doctor.
It can be given through a nasogastric tube or gastrostomy tube when necessary in case of severe inflammation of the mouth (mucositis) or if the patient is in a coma.
For Adults, the dose is 1 packet to be given by mouth every 6 hours for 20 doses, with or without food.
For children, the dose is 6.2 grams/m2 of body surface area given every 6 hours for 20 doses, with or without food.
• If there is an allergy or hypersensitivity to uridine.
• Pregnant and breastfeeding women.
• Not recommended for the non-emergent treatment of side effects associated with fluorouracil or capecitabine because it may decrease the effectiveness of these drugs.
• Should not be given after 4 days or 96hrs of administration of fluorouracil or capecitabine.
Crush the contents of one full 10-gram packet of granules to a fine powder. Add the crushed granules to 4 ounces (100 mL) of the starch-based thickening product.
Prepare the mixture at a ratio of no greater than 1 gram per 10 mL of reconstituted food while giving to pediatric patients receiving less than 10 grams.
Take this within 30 minutes of mixing.
At least 4 ounces of water should be taken to make sure that patient swallow all of the medicine.
In children, the dose should be given based on their weight.
In case of vomiting, take another full dose as soon as possible and then the next dose at a regular scheduled time.
The dose should be measured using either a scale accurate to at least 0.1 gram, or a graduated teaspoon accurate to ¼ teaspoon.
Administer full course which is 20 doses as directed by the doctor.
It can be given through a nasogastric tube or gastrostomy tube when necessary in case of severe inflammation of the mouth (mucositis) or if the patient is in a coma.
Dosage & When it is to be taken
Uridine triacetate is available as granules in 10-gram packets to be taken by mouth (orally).For Adults, the dose is 1 packet to be given by mouth every 6 hours for 20 doses, with or without food.
For children, the dose is 6.2 grams/m2 of body surface area given every 6 hours for 20 doses, with or without food.
When it is not to be taken (Contraindications)
Uridine should not be used in patients-• If there is an allergy or hypersensitivity to uridine.
• Pregnant and breastfeeding women.
• Not recommended for the non-emergent treatment of side effects associated with fluorouracil or capecitabine because it may decrease the effectiveness of these drugs.
• Should not be given after 4 days or 96hrs of administration of fluorouracil or capecitabine.
