Review the side-effects of Lutetium Lu 177 Dotatate as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Nausea, vomiting, diarrhea, stomach pain, constipation, loss of appetite
Blood: Reduced or altered counts of red blood cells, white blood cells, platelets, acute leukemia
Cardiovascular: Irregular heartbeat (atrial fibrillation), swelling of the legs and ankles, increased blood pressure
Nervous system:Dizziness, headache, taste disturbances, anxiety
Musculoskeletal: Muscle pain, back pain, pain in the legs, hands, and neck
Kidneys and Urinary Tract: Kidney dysfunction, kidney failure, urinary symptoms due to damage to the urinary tract which may include pain, urinary incontinence, urgency while passing urine and/or increased frequency
Metabolic abnormalities: Increased blood level of uric acid or sodium, low blood calcium levels, fluctuations in blood sugar or potassium level.
Others: Fatigue, fever, cough, liver dysfunction (especially in those with spread of the cancer to the liver), increased risk of cancer, hair loss, neuroendocrine hormonal crisis with symptoms that may include breathlessness, flushing, decreased blood pressure and diarrhea
• Unused medicinal products or medical waste from the treatment should be disposed of in accordance with the rules laid down by the local law and regulations authority.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Gastrointestinal: Nausea, vomiting, diarrhea, stomach pain, constipation, loss of appetite
Blood: Reduced or altered counts of red blood cells, white blood cells, platelets, acute leukemia
Cardiovascular: Irregular heartbeat (atrial fibrillation), swelling of the legs and ankles, increased blood pressure
Nervous system:Dizziness, headache, taste disturbances, anxiety
Musculoskeletal: Muscle pain, back pain, pain in the legs, hands, and neck
Kidneys and Urinary Tract: Kidney dysfunction, kidney failure, urinary symptoms due to damage to the urinary tract which may include pain, urinary incontinence, urgency while passing urine and/or increased frequency
Metabolic abnormalities: Increased blood level of uric acid or sodium, low blood calcium levels, fluctuations in blood sugar or potassium level.
Others: Fatigue, fever, cough, liver dysfunction (especially in those with spread of the cancer to the liver), increased risk of cancer, hair loss, neuroendocrine hormonal crisis with symptoms that may include breathlessness, flushing, decreased blood pressure and diarrhea
Other Precautions :
• Lutetium 177 dotatate should not be given as an intravenous bolus and is necessary to administer it according to the instructions provided.• Unused medicinal products or medical waste from the treatment should be disposed of in accordance with the rules laid down by the local law and regulations authority.
