Review the side-effects of Palbociclib as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
General: Fatigue
Gastrointestinal: Nausea, vomiting, diarrhea, decreased appetite, stomatitis (inflammation of the mucus membrane of the mouth).
Respiratory: Shortness of breath, sudden chest pain due to pulmonary embolism, bleeding from the nose (epistaxis).
Blood: Reduced counts of blood cells i.e. red blood cells, white blood cells and platelets.
Nervous system: Peripheral neuropathy (damage to the peripheral nerves).
Hair: Unusual thinning of hair or hair loss.
• Patients should be advised to avoid grapefruit juice while taking the drug as it might increase the plasma concentration of the drug.
• It is advisable that the patient does not take an extra dose of palbociclib on the same day if he/she vomits or misses the dose on that day.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
General: Fatigue
Gastrointestinal: Nausea, vomiting, diarrhea, decreased appetite, stomatitis (inflammation of the mucus membrane of the mouth).
Respiratory: Shortness of breath, sudden chest pain due to pulmonary embolism, bleeding from the nose (epistaxis).
Blood: Reduced counts of blood cells i.e. red blood cells, white blood cells and platelets.
Nervous system: Peripheral neuropathy (damage to the peripheral nerves).
Hair: Unusual thinning of hair or hair loss.
Other Precautions :
• Do not breastfeed your baby while taking palbociclib as there is no clear data on whether the drug could pass through the breastmilk and harm the baby.• Patients should be advised to avoid grapefruit juice while taking the drug as it might increase the plasma concentration of the drug.
• It is advisable that the patient does not take an extra dose of palbociclib on the same day if he/she vomits or misses the dose on that day.
