Review the side-effects of Pipecuronium as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Cardiovascular: Decreased blood pressure, decreased heart rate, chestpain, abnormal heart rhythm and thrombosis (formation of a clot in a blood vessel).
Central Nervous System: Decreased brain activity, reduced sensation of touch
Respiratory: Difficulty in breathing, respiratory depression, laryngeal muscle spasm, and lung collapse
Metabolic: Decreased blood sugar level, increased blood potassium level and creatinine level
Others: Anuria (passage of less or no urine), skin rashes, a decrease in the muscle mass and an allergic reaction including an anaphylactic reaction.
• In case of overdosage, neostigmine is used to reverse the effects of pipecuronium.
• A peripheral nerve stimulator can be used to identify the nature and degree of the neuromuscular blockade.
• Since pipecuronium contains bromide, it should be avoided inpatients who had episodes of bromide allergy.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Cardiovascular: Decreased blood pressure, decreased heart rate, chestpain, abnormal heart rhythm and thrombosis (formation of a clot in a blood vessel).
Central Nervous System: Decreased brain activity, reduced sensation of touch
Respiratory: Difficulty in breathing, respiratory depression, laryngeal muscle spasm, and lung collapse
Metabolic: Decreased blood sugar level, increased blood potassium level and creatinine level
Others: Anuria (passage of less or no urine), skin rashes, a decrease in the muscle mass and an allergic reaction including an anaphylactic reaction.
Other Precautions :
• Pipecuronium has no effect on consciousness and pain, therefore it should be always accompanied by anesthesia.• In case of overdosage, neostigmine is used to reverse the effects of pipecuronium.
• A peripheral nerve stimulator can be used to identify the nature and degree of the neuromuscular blockade.
• Since pipecuronium contains bromide, it should be avoided inpatients who had episodes of bromide allergy.
