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Side effect(s) of Sirolimus


Review the side-effects of Sirolimus as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

   Most Common
- Swelling in the extremities, high blood pressure, increased cholesterol level, constipation, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, joint pain, and decrease in platelet counts.

   Body as a Whole
- Sepsis and infections.

   Heart
- Blood clot events and fast heart rate.

   Gastrointestinal
- Mouth ulcer.

  Metabolic
- Abnormal healing, increased level of lactic dehydrogenase (LDH) and decrease in blood potassium level.

   Musculoskeletal
- Death of bone cells.

   Respiratory
- Nose bleed and lung infection.

   Skin
- Skin cancer and rash.

   Genitourinary
- Kidney inflammation.

Other Precautions :

Avoid excess dosage.

Drug Name : Sirolimus

Sirolimus(Rapamune) generic is an immunosuppressant, prescribed for preventing rejection of kidney transplants either alone or with other medications. It works by suppressing the body's immune system.


Trade Names for Sirolimus


International :


Rapamune, Siromus, Rapacan
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