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Medications and their Potential to Cause Increase 'Fatigue'(Extreme Tiredness)


This page lists all known medications that could potentially lead to 'Fatigue' as a side effect. It's important to note that mild side effects are quite common with medications. The medication(s) listed here may be used individually or as part of a broader combination therapy. The information provided is intended as a helpful resource; however, it should not replace professional medical advice. If you're concerned about 'Fatigue', it is advisable to consult a healthcare professional.
In addition to 'Fatigue', there may be other similar symptoms or signs that better match your side effect. These have also been listed below for your convenience. If you find a symptom that more closely resembles your experience, you can use this information to identify potential medications that might be the cause.

Drugs with the Side Effect - Fatigue

Pasireotide


Most other Common Side Effects: Diarrhea, nausea, hyperglycemia, gallstone, headache, abdominal pain

Abacavir Sulfate and Lamivudine


Most other Common Side Effects: Hypersensitivity, sleeplessness, depression, headache, migraine, uneasiness, dizziness, nausea, vomiting, diarrhea, rash, fever, abdominal pain, abnormal dreams, anxiety, cough or Inflammation of the pharynx, eye problems, enlarged lymph nodes and swollen ankles

Abacavir Sulfate, Lamivudine and Zidovudine


Most other Common Side Effects: Nausea, vomiting, headache, uneasiness, diarrhea, fever, chills, depressive disorders, musculoskeletal pain, rash, throat infections, anxiety

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Ado-trastuzumab Emtansine


Most other Common Side Effects: nausea, muscle and bone pain, decrease in platelet counts, headache, increased level of liver enzymes and constipation

Agalsidase


Most other Common Side Effects: Chills, fever, feeling hot or cold, difficulty in breathing, nausea, swelling of the face, mouth, and throat, flushing, headache, vomiting, tingling, itching, pain in extremity, high blood pressure, chest pain, throat tightness, abdominal pain, dizziness, fast heart rate, nasal congestion, diarrhea, muscle pain, back pain, pallor, slow heart rate, hives, low blood pressure, face swelling, rash, and drowsiness

Allopurinol


Most other Common Side Effects: Chills, fever, feeling hot or cold, difficulty in breathing, nausea, swelling of the face, mouth, and throat, flushing, headache, vomiting, tingling, itching, pain in extremity, high blood pressure, chest pain, throat tightness, abdominal pain, dizziness, fast heart rate, nasal congestion, diarrhea, muscle pain, back pain, pallor, slow heart rate, hives, low blood pressure, face swelling, rash, and drowsiness

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Amlodipine Hydrochlorothiazide and Olmesartan


Most other Common Side Effects: Dizziness, lightheadedness, swelling in the extremities, headache, inflammation of the nasopharynx, muscle spasms, nausea, upper respiratory tract infection, diarrhea, urinary tract infection, joint swelling

Amsacrine


Most other Common Side Effects: sore mouth and throat, loss of fertility, absence of menstrual period, decrease in the number of healthy white blood cells, red blood cells or platelets in the blood

Anthrax Vaccine Adsorbed


Most other Common Side Effects: Injection site tenderness, pain, warmth, muscle pain, arm motion limitation

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Axitinib Tablets


Most other Common Side Effects: Diarrhea, high blood pressure, decreased appetite, nausea, loss of voice, hand-foot syndrome (palmar-plantar erythrodysesthesia), weight loss, vomiting, weakness and constipation

Azelastine


Most other Common Side Effects: Bitter taste, headache, drowsiness, nasal burning, inflammation of pharynx/nose, dry mouth, sneezing, nausea, dizziness, nosebleed and increased weight

Bendamustine Hydrochloride


Most other Common Side Effects: Fever, nausea and vomiting, weakness, uneasiness, dry mouth, drowsiness, cough, constipation, headache and mouth ulcer

Bexarotene


Most other Common Side Effects: Underactive thyroid, headache, weakness, rash, anemia, nausea, infection, swelling in the extremities, abdominal pain, dry skin, diarrhea, liver function test abnormalities, muscle spasm and confusion

Bezafibrate


Most other Common Side Effects: Gastrointestinal upset, nausea, vomiting, itching, hives, muscle pain, dizziness, hair loss, impotence, fainting

Bisoprolol


Most other Common Side Effects: Abdominal cramps, diarrhea, dizziness, depression, headache, nausea, impotence, slow heart rate, low blood pressure, numbness, tingling, cold extremities, sore throat and shortness of breath

Boceprevir


Most other Common Side Effects: anemia, nausea/vomiting, headache, and sensory loss

Bosutinib



Most other Common Side Effects: Diarrhea, nausea, decrease in platelets, vomiting, abdominal pain, rash, anemia, pyrexia

Brentuximab Vedotin


Most other Common Side Effects: Decrease in white blood cells, anemia, peripheral sensory neuropathy, nausea, fever, rash, diarrhea and pain

Cabozantinib


Most other Common Side Effects: Diarrhea, mouth ulcer, palmar-plantar erythrodysesthesia syndrome (PPES), decreased weight, decreased appetite, nausea, mouth pain, hair color changes, taste disorder, high blood pressure, abdominal pain, and constipation

Captopril


Most other Common Side Effects: Diarrhea, mouth ulcer, palmar-plantar erythrodysesthesia syndrome (PPES), decreased weight, decreased appetite, nausea, mouth pain, hair color changes, taste disorder, high blood pressure, abdominal pain, and constipation

Carbamazepine


Most other Common Side Effects: Diarrhea, mouth ulcer, palmar-plantar erythrodysesthesia syndrome (PPES), decreased weight, decreased appetite, nausea, mouth pain, hair color changes, taste disorder, high blood pressure, abdominal pain, and constipation

Cladribine


Most other Common Side Effects: nausea, and injection site reactions

Clonidine


Most other Common Side Effects: Dry mouth, drowsiness, headache, lethargy, sedation, sleeplessness, dizziness, impotence/sexual dysfunction, dry throat, constipation, tingling, nausea and vomiting

Cyclobenzaprine


Most other Common Side Effects: Drowsiness, headache, dizziness, blurred vision, nausea, abnormal taste, palpitations, tremor, dry throat, pimples, attention disturbances, sleeplessness, constipation and indigestion

Decitabine


Most other Common Side Effects: Anemia, decrease in white blood cells and platelets, fever, nausea, cough, constipation, diarrhea, and sugar

Denileukin Diftitox


Most other Common Side Effects: Fever, nausea, rigors, vomiting, diarrhea, headache, swelling in the extremities, cough, difficulty in breathing and itching

Denosumab


Most other Common Side Effects: decreased level of phosphate and calcium in blood, nausea, diarrhea, headache and cough

Dexrazoxane


Most other Common Side Effects: Hair loss, nausea, vomiting, uneasiness, loss of appetite, mouth ulcer, fever, infection, diarrhea, pain at injection site, sepsis, nerve damage, redness, vein inflammation, esophagus inflammation, indigestion, bleeding and hives

Diazepam


Most other Common Side Effects: Drowsiness

Didanosine


Most other Common Side Effects: Inflammation of pancreas, diarrhea, nausea, vomiting, abdominal pain, headache, rash, urea in blood, liver failure and blurred vision

Diltiazem


Most other Common Side Effects: Inflammation of pancreas, diarrhea, nausea, vomiting, abdominal pain, headache, rash, urea in blood, liver failure and blurred vision

Drospirenone and Estradiol



Most other Common Side Effects: Irregular periods, nausea, vomiting, breast tenderness, headache, decreased libido and increased weight

Efavirenz


Most other Common Side Effects: Dizziness, nausea, headache, sleeplessness and vomiting

Elosulphase Alpha


Most other Common Side Effects: Dizziness, nausea, headache, sleeplessness and vomiting

Emtricitabine


Most other Common Side Effects: Headache, diarrhea, nausea, dizziness, depression, sleeplessness, abnormal dreams, rash, abdominal pain, weakness, increased cough, and nose inflammation

Enzalutamide


Most other Common Side Effects: Weakness, back pain, diarrhea, joint pain, hot flush, swelling in the extremities, muscle pain, headache, upper respiratory infection, muscle weakness, dizziness, sleeplessness, lower respiratory infection, spinal cord compression, cauda equina syndrome, blood in urine, tingling, anxiety, and high blood pressure

Eprosartan Mesylate Hydrochlorothiazide


Most other Common Side Effects: Dizziness, headache, back pain, muscle pain, upper respiratory tract infection, sinusitis, viral infection

Eribulin Mesylate


Most other Common Side Effects: Decrease in white blood cells, anemia, weakness, hair loss, nerve disease, nausea, and constipation

Fluoxetine and Olanzapine


Most other Common Side Effects: Disturbance in attention, dry mouth, excessive sleepiness, increased appetite, swelling in the extremities, drowsiness, tremor, blurred vision , and increased weight

Frovatriptan


Most other Common Side Effects: Dizziness, tingling, headache, dry mouth, flushing, hot or cold sensation and chest pain

Gemcitabine


Most other Common Side Effects: Nausea, vomiting, diarrhea, pain/redness at the injection site and flu-like symptoms (muscle pain, fever, headache

Ibritumomab Tiuxetan


Most other Common Side Effects: Reduction in the number of blood cells, abdominal pain, nausea, cold, weakness, diarrhea, cough and fever

Imidapril


Most other Common Side Effects: Dizziness, headache, tingling, impotence and sleep disturbances

Interferon Beta 1A


Most other Common Side Effects: Influenza-like symptoms (headache, fever, rigors, chest pain, back pain, muscle pain), abdominal pain, depression, raised alkaline phosphatase, and blood disorder

Interferon Gamma 1B


Most other Common Side Effects: Fever, headache, rash, chills, injection site redness, tenderness, diarrhea, vomiting, nausea and muscle/joint pain

Ipilimumab


Most other Common Side Effects: diarrhea, itching, rash and intestinal inflammation

Isradipine


Most other Common Side Effects: Headache, dizziness or lightheadedness, flushing, constipation, abdominal discomfort and rash

Lisinopril and Hydrochlorothiazide


Most other Common Side Effects: Dizziness, headache, cough, diarrhea, nausea, upper respiratory infection, muscle cramps, weakness, tingling, low blood pressure, vomiting, indigestion, rash, impotence

Loratadine


Most other Common Side Effects: giddiness, dizziness, dry mouth, headache, nausea and drowsiness

Mefloquine


Most other Common Side Effects: Dizziness, muscle pain, nausea, fever, headache, vomiting, chills, diarrhea, skin rash, abdominal pain, loss of appetite and ringing in the ear

Methimazole


Most other Common Side Effects: Dizziness, muscle pain, nausea, fever, headache, vomiting, chills, diarrhea, skin rash, abdominal pain, loss of appetite and ringing in the ear

Methyltestosterone


Most other Common Side Effects: Dizziness, muscle pain, nausea, fever, headache, vomiting, chills, diarrhea, skin rash, abdominal pain, loss of appetite and ringing in the ear

Moexipril HCl Hydrochlorothiazide Tablets


Most other Common Side Effects: Cough

Moricizine


Most other Common Side Effects: Dizziness, nausea, headache, palpitations, difficulty in breathing, congestive heart failure, musculoskeletal pain, diarrhea, dry mouth and death

Naltrexone


Most other Common Side Effects: Constipation, abdominal, joint and muscle pain

Natalizumab


Most other Common Side Effects: Headache, joint pain, urinary tract infection, lower respiratory tract infection, stomach inflammation, vaginal inflammation, depression, pain in extremity, abdominal discomfort, diarrhea, and rash

Nilotinib


Most other Common Side Effects: Rash, itching, headache, nausea, muscle pain, upper abdominal pain, hair loss, constipation, diarrhea, dry skin, muscle spasms, joint pain and abdominal pain

Ofatumumab


Most other Common Side Effects: Decrease in white blood cells, pneumonia, fever, cough, diarrhea, anemia, difficulty in breathing, rash, nausea, vomiting, lung inflammation, and upper respiratory tract infections

Oxaliplatin


Most other Common Side Effects: Peripheral sensory neuropathies, decrease in platelet counts, nausea, vomitting and diarrhea

Oxcarbazepine


Most other Common Side Effects: Dizziness, drowsiness, double vision, running nose, nausea, vomiting, ataxia, abnormal vision, sore throat, abdominal pain, tremor, indigestion, abnormal gait

Palonosetron


Most other Common Side Effects: Headache, constipation, diarrhea, dizziness, abdominal pain and sleeplessness

Panitumumab Injection


Most other Common Side Effects: Decreased level of manganese in blood, nail disorder, abdominal pain, nausea, and diarrhea

Pazopanib


Most other Common Side Effects: Diarrhea, high blood pressure, hair color change, nausea, loss of appetite and vomiting

Penicillamine


Most other Common Side Effects: Diarrhea, high blood pressure, hair color change, nausea, loss of appetite and vomiting

Perampanel


Most other Common Side Effects: Dizziness, drowsiness, headache, irritability

Pertuzumab


Most other Common Side Effects: Diarrhea, hair loss, decrease in white blood cells, stomach upset, rash, damage to the nerves

Plerixafor Injection


Most other Common Side Effects: Diarrhea, nausea, injection site reactions, headache, joint pain, dizziness, and vomiting

Pomalidomide


Most other Common Side Effects: weakness, decrease in white blood cells, anemia, constipation, nausea, diarrhea, difficulty in breathing, upper-respiratory tract infections, back pain and fever

Ponatinib


Most other Common Side Effects: High blood pressure, rash, abdominal pain, headache, dry skin, constipation, joint pain, nausea and fever

Pralatrexate Solution


Most other Common Side Effects: Decrease in platelet counts and white blood cells, inflammation of mucous, nausea, anemia, constipation, fever, fluid retention, cough, nose bleed, vomiting, diarrhea, difficulty in breathing, loss of appetite, rash, itching, throat pain, liver function test abnormal, abdominal pain, pain in extremity, back pain, night sweats, weakness, fast heart rate

Propafenone


Most other Common Side Effects: Dizziness, chest pain, palpitations, taste disturbance, blurred vision, difficulty in breathing, nausea, constipation, anxiety, upper respiratory tract infection, influenza, first-degree heart block, and vomiting

Quinapril


Most other Common Side Effects: Dizziness, coughing, nausea , vomiting, chest pain, low blood pressure, difficulty in breathing, diarrhea, headache, muscle pain, rash and back pain

Regorafenib


Most other Common Side Effects: Weakness, decreased appetite and food intake, Hand-foot skin reaction (HFSR) (palmar-plantar erythrodysesthesia [PPE]), diarrhea, weight loss, and infection

Retinol


Most other Common Side Effects:

Ribavirin


Most other Common Side Effects:

Rizatriptan


Most other Common Side Effects: Dizziness, sleeplessness, tiredness, pain or pressure sensation

Rosiglitazone


Most other Common Side Effects: Upper respiratory tract infection, injury, headache, back pain, increased/decreased blood sugar, sinusitis, diarrhea

Rosiglitazone and Metformin


Most other Common Side Effects: Upper respiratory tract infection, diarrhea, injury, anemia, headache, sinusitis, back pain, viral infection, joint pain

Sipuleucel-T Suspension


Most other Common Side Effects: Chills, fever, back, nausea, joint ache, and headache

Streptomycin


Most other Common Side Effects: Chills, fever, back, nausea, joint ache, and headache

Sulfamethoxazole


Most other Common Side Effects: Chills, fever, back, nausea, joint ache, and headache

Sunitinib


Most other Common Side Effects: weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, joint pain, cough, difficulty in breathing, loss of appetite, and bleeding

Tolcapone


Most other Common Side Effects: Movement disorder, nausea, sleep disorder, involuntary movements, excessive dreaming, loss of appetite, muscular cramps, orthostatic complaints, drowsiness, diarrhea, confusion, dizziness, headache, hallucinations, vomiting, constipation, upper respiratory tract infection, falling, increased sweating, urinary tract infection, dry mouth, abdominal pain and urine discoloration

Trifluoperazine


Most other Common Side Effects: Drowsiness, dizziness, skin reactions, rash, dry mouth, sleeplessness, absence of menstrual periods, muscular weakness, loss of appetite, spontaneous secretion of milk, blurred vision and neuromuscular (extrapyramidal) reactions

Vandetanib


Most other Common Side Effects: Diarrhea, rash, acne, nausea, high blood pressure, headache, decreased appetite, and abdominal pain

Vemurafenib Tablet


Most other Common Side Effects: Joint pain, rash, hair loss, photosensitivity reaction, nausea, itching, and skin papilloma

Verapamil


Most other Common Side Effects: Constipation, headache, upper respiratory infection, dizziness, swelling in the extremities, nausea, elevated liver enzymes, raised alkaline phosphatase, slow heart rate, tingling, flushing and low blood pressure

Vigabatrin


Most other Common Side Effects: Headache, drowsiness, dizziness, seizures, increased weight, upper respiratory tract infection, visual defects, depression, tremor, night blindness, nausea, diarrhea, memory loss, sleeplessness, irritability, abnormal coordination, blurred vision, double vision, vomiting, influenza, fever and rash

Find drugs that can cause other symptoms like 'Fatigue'

References

  1. https://www.fda.gov/drugs/information-consumers-and-patients-drugs/finding-and-learning-about-side-effects-adverse-reactions
  2. https://nctr-crs.fda.gov/fdalabel/ui/search
  3. https://dailymed.nlm.nih.gov/dailymed/
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