Abnormal processes

Infectious, Inflammatory, and Immunologic disorders

• Infections of the blood, Reticuloendothelial system, and lymphatics
• Allergic and anaphylactic reactions and other immunopathologic
  
  mechanisms
• Acquired disorders of immune deficiency
• Autoimmunity and autoimmune diseases (eg, Coombs positive hemolytic anemia, pernicious anemia, cryoglobulinemias, ITP)
• Anemia of chronic disease
• Transfusion complications, transplant rejection

Traumatic and mechanical injury (eg, mechanical injury to erythrocytes, splenic rupture)

Neoplastic disorders (eg, lymphoma, leukemia, multiple myeloma)

Metabolic and regulatory disorders,

including acquired and congenital

• Anemias and cytopenias (eg, iron deficiency anemia, hemoglobinopathies, hereditary spherocytosis)
• Cythemia
• Hemorrhagic and hemostatic disorders (eg, coagulopathies, DIC)
• Bleeding secondary to platelet disorders (eg, von Willebrand)

Vascular and endothelial disorders (eg, effects and complications of splenectomy, hypersplenism, TTP, hemolytic-uremic syndrome)

Systemic disorders affecting the hematopoietic and lymphoreticular system (eg, nutritional deficiencies, systemic lupus erythematosus)

Idiopathic disorders

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