Biochemistry and Molecular Biology

Gene expression: transcription, including defects

Transcription of DNA into RNA, enzymatic reactions, RNA, RNA degradation
Regulation: cis-regulatory elements, transcription factors, enhancers, promoters, silencers, represents, splicing

Gene expression: translation, including defects

The genetic code
Structure and function of tRNA
Structure and function of ribosomes
Protein synthesis
Regulation of translation
Post-translation modifications, including phosphorylation,
addition of CHO units
Protein degradation

Structure and function of proteins

Principles of protein structure and folding
Enzymes: kinetics, reaction mechanisms
Structural and regulatory proteins: ligand binding, self-assembly
Regulatory properties

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