Pharmacodynamic and pharmacokinetic processes

General principles

• Pharmacokinetics: absorption, distribution, metabolism, excretion, dosage intervals
• Mechanisms of drug action, structure-activity
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  relationships
• Concentration- and dose-effect relationships (eg, efficacy, potency), types of agonists and antagonists and their actions
• Individual factors altering pharmacokinetics and pharmacodynamics (eg, age, gender, disease, tolerance, compliance, body weight, metabolic proficiency, pharmacogenetics)
• Drug side effects, overdosage, toxicology
• Drug interactions
• Regulatory issues (eg, drug development, approval, scheduling)
• General
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  properties of autacoids, including peptides and analogs, biogenic amines, prostanoids and their inhibitors, and smooth muscle/endothelial autacoids
• General principles of autonomic pharmacology
• General properties of antimicrobials, including mechanisms of action and resistance
• General properties of antineoplastic agents and immunosuppressants, including drug effects on rapidly dividing mammalian cells

• << Multisystem processes
• Microbial biology and infection >>