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Quantitative Methods

Fundamental concepts of measurement

  • scales of measurement
  • Distribution, central tendency, variability, probability
  • Disease prevalence and incidence
  • Disease

    outcomes (eg, fatality rates)
  • Associations (eg, correlation and covariance)
  • Health impact (eg, risk differences and ratios)
  • Sensitivity, specificity, predictive values

Fundamental concepts of study design

  • Types of experimental studies (eg, clinical trials, community intervention trials)
  • Types of observational studies (eg, cohort, case-control, cross-sectional, case series, community surveys)
  • Sampling
    and sample size
  • Subject selection and exposure allocation (eg, randomization, stratification, self-selection, systematic assignment)
  • Outcome assessment
  • Internal and external validity

Fundamental concepts of hypothesis testing and statistical inference

  • Confidence intervals
  • Statistical significance and Type I error
  • Statistical power and Type II error
  • Hematopoietic and Lymphoreticular Systems
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