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In the UK, about 37% cases are preventable. Pancreatic cell develop mutations in the DNA, which leads to rapid replications of pancreatic cell that develops into tumor.
BRCA1 or BRCA2 and CDH1 gene increases the risk of pancreatic cancer. Pancreatic cancer is sometimes known as “Silent Killer”, because it does not cause any symptoms in the early stages.
Pancreas is located deep in the abdominal cavity. Most pancreatic cancer are adenocarcinoma. Pancreatic cancer grows without any signs of symptoms. Pancreas has both endocrine and exocrine function. Exocrine glands secretes digestive juices and endocrine gland called as Islets of Langerhans, involved in secretion of certain hormone such as insulin and glucagon in bloodstream. Crohn’s disease, gastric ulcers and gum disease may also increase the risk of pancreatic cancer.
Pancreatic Cancer Types include
1. Exocrine Pancreatic Cancer
- Cystic tumors: Fluid filled sac in the pancreas some of these are cancerous
- Acinar cells carcinomas: Rare form.Tumors starts from the cell that makes pancreatic juices
3. Rare type of Pancreatic Cancer
- Pancreatoblastoma: Rare tumor. It occurs in children
- Sarcomas of the pancreas
- Lymphoma: Cancer occur in the lymphatic tissues
Pancreatic cancers have poor diagnosis