NEW YORK, Sept. 17, 2024
NEW YORK, Sept. 17, 2024 /PRNewswire/ -- Report with the AI impact on market trends- The global ursodeoxycholic acid market size is estimated to grow by USD 463.2 million from 2024-2028, according to Technavio. The market is estimated to grow at a CAGR of 12.16% during the forecast period. Rise in number of liver transplants is driving market growth, with a trend towards growing demand for combination therapies. However, expiry of patents on branded drugs leading to competition with manufacturers of generics poses a challenge. Key market players include Abil Chempharma Pvt. Ltd., Anant Pharmaceuticals Pvt. Ltd., Axplora, Cerata Pharmaceuticals LLP, Changde Yungang Biotechnology Co. Ltd., Daewoong Bio Inc., Dipharma Francis S.r.l., Glenmark Pharmaceuticals Ltd., ICE S.p.a., JSC Grindeks, Kimia Biosciences Ltd., Merck KGaA, Mitsubishi Chemical Group Corp., Octavius Pharma Pvt. Ltd., Osmopharm SA, Panjin Hengchanglong Pharmaceutical Co. Ltd., Suzhou Tianlu Bio Pharmaceutical Co. Ltd., Tianjin NWS Biotechnology and Medicine Co. Ltd., Travere Therapeutics Inc., and Zhongshan Belling Biotechnology Co. Ltd..
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Forecast period
2024-2028
Base Year
2023
Historic Data
2018 - 2022
Segment Covered
Type (Synthetic ursodeoxycholic acid and Extraction ursodeoxycholic acid), Application (Pharmacy products and Health products), and Geography (North America, Europe, Asia, and Rest of World (ROW))
Region Covered
North America, Europe, Asia, and Rest of World (ROW)
Key companies profiled
Abil Chempharma Pvt. Ltd., Anant Pharmaceuticals Pvt. Ltd., Axplora, Cerata Pharmaceuticals LLP, Changde Yungang Biotechnology Co. Ltd., Daewoong Bio Inc., Dipharma Francis S.r.l., Glenmark Pharmaceuticals Ltd., ICE S.p.a., JSC Grindeks, Kimia Biosciences Ltd., Merck KGaA, Mitsubishi Chemical Group Corp., Octavius Pharma Pvt. Ltd., Osmopharm SA, Panjin Hengchanglong Pharmaceutical Co. Ltd., Suzhou Tianlu Bio Pharmaceutical Co. Ltd., Tianjin NWS Biotechnology and Medicine Co. Ltd., Travere Therapeutics Inc., and Zhongshan Belling Biotechnology Co. Ltd.
Key Market Trends Fueling Growth
Ursodeoxycholic acid (UDCA) is a bile acid utilized extensively as a therapeutic agent for various liver disorders and diseases, including Primary Biliary Cholangitis (PBC) and gallstone dissolution. The global ursodeoxycholic acid market growth is driven by the increasing preference for combination therapies in treating liver diseases. Combination therapies involve using two or more medications concurrently to enhance treatment efficacy and improve patient outcomes. In the context of liver disorders, UDCA in combination with other drugs, such as prednisolone or mycophenolate mofetil, has proven to be more effective in managing disease progression and alleviating symptoms. For instance, a study published in the Journal of Hepatology reported a higher biochemical response rate in PBC patients when UDCA was combined with prednisolone. Another study in the American Journal of Gastroenterology demonstrated improved liver function and reduced disease progression risk in PSC patients using UDCA and mycophenolate mofetil. Ongoing research and development activities focused on novel UDCA-based combination therapies will further fuel market growth. Additionally, the rising global prevalence of liver diseases and growing awareness of combination therapies' benefits will boost UDCA demand and market expansion during the forecast period.
The Ursodeoxycholic Acid (UDCA) market is experiencing significant growth due to its effectiveness in addressing various liver disorders, including cholestasis. UDCA-based therapeutics have become popular oral therapies in pharmacies and health product stores for treating liver diseases like primary biliary cholangitis and gallstones. The use of nanotechnology and biotechnology in producing UDCA medications has improved their bioavailability and efficacy. However, negative side effects such as diarrhea, dry skin, itching, headache, disturbed sleep, and vomiting are common concerns for patients. The healthcare system continues to prioritize liver-protective properties of UDCA in managing inflammation and improving liver function. Both branded and generic versions of UDCA medications are available in the market, offering patients and healthcare providers various strengths and costs. UDCA's cholesterol gallstones and primary sclerosing cholangitis applications further expand its market reach.
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Market Challenges
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Segment Overview
This ursodeoxycholic acid market report extensively covers market segmentation by
1.1 Synthetic ursodeoxycholic acid- Synthetic ursodeoxycholic acid (UDCA) is produced through chemical processes using various precursor compounds and is a preferred choice for pharmaceutical applications due to its consistent and controlled quality. The manufacturing process enables precise control over purity and composition, ensuring highest levels of efficacy. Advanced synthesis methods, such as enzymatic synthesis, offer milder reaction conditions, higher selectivity, and reduced environmental impact. Products like Ursocol from Sun Pharmaceutical and Urosod from Dr. Falk Pharma are widely used for gallstones, PBD, and liver disorders. Synthetic UDCA's longer shelf life and availability in different dosages and formulations make it convenient for researchers to develop new formulations and drug delivery systems. Its advantages make synthetic UDCA a suitable alternative for pharmaceutical companies and researchers, leading to increased demand and growth of the global ursodeoxycholic acid market.
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Research Analysis
Ursodeoxycholic acid (UDCA) is a bile acid that plays a crucial role in promoting liver health and aiding in the treatment of various liver diseases. It is particularly effective in conditions such as primary biliary cholangitis, where it helps reduce inflammation and improve liver function. UDCA is available in both branded and generic versions, with strengths ranging from 150mg to 1000mg. Patients and healthcare providers often prescribe UDCA to manage gallstones, gastroesophageal varices, cirrhosis, primary biliary cirrhosis, and cholestasis. UDCA is available in liquid form and as hydrophobic bile acids. UDCA-based therapeutics are also being explored for the treatment of liver disorders, including cystic fibrosis. Taurine, another amino acid, is sometimes used in combination with UDCA to enhance its therapeutic effects. The development of UDCA-based therapies through nanotechnology and biotechnology is also an emerging trend in the healthcare industry.
Market Research Overview
Ursodeoxycholic Acid (UDCA) is a bile acid with liver-protective properties, primarily used in the treatment of various liver diseases, including primary biliary cholangitis, gallstones, and primary sclerosing cholangitis. UDCA's role in liver health is essential due to its anti-inflammatory and anti-apoptotic effects, which help in mitigating mitochondrial dysfunction and promoting cell survival pathways. UDCA comes in both branded and generic versions, with strengths varying from 150mg to 1200mg. Patients and healthcare providers benefit from UDCA's ability to dissolve cholesterol gallstones and improve liver function. However, UDCA's slow action and potential for stone recurrence are pitfalls. Raw material shortages and regulatory approval processes pose challenges in ensuring a consistent supply of high-purity UDCA. UDCA is available as a liquid, hydrophobic bile acid, and is used in the treatment of gastroesophageal varices, cirrhosis, and primary biliary cirrhosis. Its use extends to the treatment of cystic fibrosis and cholestatic liver disorders, such as jaundice. UDCA-based therapeutics are also explored in the field of nanotechnology and biotechnology. Despite its benefits, UDCA may cause negative side effects, including diarrhea, dry skin, itching, headache, disturbed sleep, and vomiting. These side effects can be managed through careful dosage form selection and stringent quality control measures. In conclusion, UDCA plays a vital role in the healthcare system, particularly in the treatment of various liver disorders. Its liver-protective properties, anti-inflammatory effects, and ability to dissolve cholesterol gallstones make it an essential medication for patients. However, challenges such as raw material shortages, regulatory approval processes, and negative side effects must be addressed to ensure consistent, high-quality UDCA for patients.
Table of Contents:
1 Executive Summary2 Market Landscape3 Market Sizing4 Historic Market Size5 Five Forces Analysis6 Market Segmentation
7 Customer Landscape8 Geographic Landscape9 Drivers, Challenges, and Trends10 Company Landscape11 Company Analysis12 Appendix
About Technavio
Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions.
With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.
Contacts
Technavio ResearchJesse MaidaMedia & Marketing ExecutiveUS: +1 844 364 1100UK: +44 203 893 3200Email: [email protected]: www.technavio.com/
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SOURCE Technavio
