According to the American Diabetes Association, 29.1 million people in the U.S. had diabetes in 2012. Each year, 1.4 million more people in the U.S. are diagnosed with diabetes. At that same point in time, approximately 86 million Americans over the age of 20 had pre-diabetes, up from 79 million in 2010. Blood glucose levels and fasting insulin were repeatedly proven as predictors of weight loss and maintenance success in people with pre-diabetes and diabetes. Evaluated across six major interventional diet studies utilizing a variety of nutrition strategies, these biomarkers were repeatedly proven as predictors of weight loss and maintenance success.