Sickle cell disease is a genetic condition that affects the hemoglobin in red blood cells. Hemoglobin is a pigment which gives the blood its red color. It picks up oxygen from the lungs and carries it to various parts of the body, and also carries carbon dioxide in the reverse direction. The U.S. Food and Drug Administration (FDA) has approved the use of an oral powder formulation of L-glutamine for the treatment of sickle cell disease.