Microvascular Disease Linked to Increased Risk of Leg Amputation

Microvascular disease in blood vessels of the eye (retinopathy) or kidney (nephropathy) may be markers of microvascular disease in other parts of the body as well. Patients suffering from both microvascular disease and peripheral arterial disease (narrowing of lower limb vessels) have the highest risk of amputation and need urgent interventions to prevent the same.