Restoring a tumor suppressor gene p16 could be a promising new target for treating a brain tumor, finds a new study from the Ann & Robert H. Lurie Children's Hospital of Chicago. The new study published in the Molecular Cancer Research has revealed that the tumor suppressor gene p 16 can be turned off by a histone mutation and is found to be responsible for up to 70% of the childhood brain tumors called Diffuse Intrinsic Pontine Glioma (DIPG).