Scratch That Itch: Brain Mechanism Identified

Periaqueductal gray matter, an area in the deeper portion of the brain produces a neurotransmitter called glutamate and a neuropeptide called tachykinin 1 (Tac1). Destroying Tac1 producing neurons decreases itch-induced scratching. This may give rise to new treatment targets and development of newer and more effective therapies for chronic itching.

How does the brain know when to scratch that itch? Periaqueductal gray matter is an area in the deeper portion of the brain. Tachykinin 1 (Tac1) is produced by the periaqueductal gray matter. Destroying Tac1 producing neurons decreases itch-induced scratching. Helps develop effective treatments for chronic itching.

Scratch That Itch: Brain Mechanism Identified

An area in the brain that may be involved in production of chronic itching (pruritis) and scratching, which has remained unclear until recently has now been identified by scientists. Read More

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