Immunosuppression and Risk of Non Hodgkins Lymphoma (NHL)

Immunosuppression and Risk of Non Hodgkins Lymphoma (NHL)

Individuals who are immuno-suppressed e.g. those with AIDS have more risk to develop.

Non Hodgkin's Lymphoma (NHL) than others. They are-

•  Those who have undergone an organ transplant, especially those who are in the first year after a transplant.
•  Those with certain types of inherited immune deficiency syndromes. The following list of familial immune deficiencies with a predisposition for Lymphomas has been adapted from Chapters 19, 21, 45, and 47 of Magrath's text, The Non-Hodgkin's Lymphomas (1997):
•  X-linked severe combined immunodeficiency (SCID).
•  Omenn's syndrome.
•  Purine nucleoside phosphorylase deficiency.
•  Familial immunodeficiency appears to predispose certain families to more than the expected incidence of NHL
•  X-linked agammaglobulinemia.
•  Ig-A deficiency.

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•  Common variable immune deficiency.
•  X-linked hyper-IgM syndrome.
•  IgG subclass deficiency.
•  Wiskott-Aldrich syndrome.
•  Ataxia telangiectasia.
•  DiGeorge syndrome
•  Hyper-IgE syndrome.
•  X-linked lymphoproliferative syndrome.
•  Chediak-Higashi syndrome.
•  Bloom's syndrome.
•  Enteropathy-associated T-cell lymphoma among northern Europeans.

Hashimoto's thyroiditis (for MALT lymphomas).