Immunosuppression and Risk of Non Hodgkins Lymphoma (NHL)
Individuals who are immuno-suppressed e.g. those with AIDS have more risk to develop.
Non Hodgkin's Lymphoma (NHL) than others. They are-
- Those who have undergone an organ transplant, especially those who are in the first year after a transplant.
- Those with certain types of inherited immune deficiency syndromes. The following list of familial immune deficiencies with a predisposition for Lymphomas has been adapted from Chapters 19, 21, 45, and 47 of Magrath's text, The Non-Hodgkin's Lymphomas (1997):
- X-linked severe combined immunodeficiency (SCID).
- Omenn's syndrome.
- Purine nucleoside phosphorylase deficiency.
- Familial immunodeficiency appears to predispose certain families to more than the expected incidence of NHL
- X-linked agammaglobulinemia.
- Ig-A deficiency.
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- Common variable immune deficiency.
- X-linked hyper-IgM syndrome.
- IgG subclass deficiency.
- Wiskott-Aldrich syndrome.
- Ataxia telangiectasia.
- DiGeorge syndrome
- Hyper-IgE syndrome.
- X-linked lymphoproliferative syndrome.
- Chediak-Higashi syndrome.
- Bloom's syndrome.
- Enteropathy-associated T-cell lymphoma among northern Europeans.
Hashimoto's thyroiditis (for MALT lymphomas).
