Research & Clinical Trials - Non-Hodgkins Lymphoma (NHL)
Several drugs for Non Hodgkins lymphoma being researched are in the clinical trial phase.
Malignant tumor cell surface have different antigens when compared to normal cells. Using this fact to advantage, Monoclonal Antibodies (MAB) were developed in the nineties for the treatment of NHL. There are newer MABs that are being invented all the time and tested by conducting clinical trials.
A Phase II, single arm study to test T -cell immunotherapy in individuals with indolent non-Hodgkin#$#s lymphoma (NHL) is underway. The candidates for the study are those with relapsed or refractory disease, after receiving 1- 4 prior regimens. Patients are administered Xcellerated T Cells TM, a T cell product, to enhance immune responses against tumors. The primary aim of the study is to assess the efficacy of these Xcellerated T Cells in patients suffering from indolent NHL. The study also aims at evaluating the safety of the therapy in the subject population.
Several clinical trials are assessing the effectiveness of Radioimmunotherapy as a first treatment option and also as a treatment prior to stem cell therapy.
I am a new nonhodgkins lymphoma stage 2 patient. I would love to visit with others that are in the processs of treatment. Carol
Hi , my father is corrrectly being diagnosed with NHL case of stage III. He has large B cell type lymphoma , with swelling in neck area. He is receiving his 4th chemotherapy , and is fit from exterior. How many chemo shots youhave undertaken. Can you please share your experience ?
I was not aware that the NHL can arise in the brain. I thought that the brain area was a priviledged site, an area that is in no contact with our immune system [blood and lymphatics]. Please explain further.
Frequent use of phenoxyacetic acid herbicides, in particular, 2,4-dichlorophenoxyacetic acid, has been associated with 2- to 8-fold increases of NHL in studies conducted in Sweden, Kansas, Nebraska, Canada, and elsewhere.