Biopsies are obtained from the different skin layers
A shave biopsy generally involves obtaining tissue specimens from the thin outer layer of skin, called the epidermis.
A punch biopsy generally involves obtaining tissue specimens from the epidermis. However, in some cases, a punch biopsy involves the dermis and subcutaneous tissue.
An Incisional biopsy generally involves obtaining tissue specimens from the deepest layer of skin, called the subcutaneous tissue.
