Environ Sci Pollut Res Int 2020 Feb 01
Methanolic extract of Ephedra alata ameliorates cisplatin-induced nephrotoxicity and hepatotoxicity through reducing oxidative stress and genotoxicity.
Sioud F, Ben Toumia I, Lahmer A, Khlifi R, Dhaouefi Z, Maatouk M, Ghedira K, Chekir-Ghedira L
Cisplatin (CP) is a powerful anticancer agent used in the treatment of a diverse type of cancers. Oxidative stress is one of the most important side e ...
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Source: PubMed
Amino Acids 2020 Feb 01
Mobility of water and of protein atoms at the protein-water interface, monitored by anisotropic atomic displacement parameters, are largely uncorrelated.
Carugo O
A non-redundant set of 231 protein crystal structures refined at a resolution better than (or equal to) 1 Å was extracted from the Protein Data Bank a ...
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Source: PubMed
Amino Acids 2020 Feb 01
Human cationic amino acid transporters are not affected by direct nitros(yl)ation.
Hobbach AJ, Closs EI
A direct inhibiting effect of NO on the function of CAT-1 and -2A has been postulated to occur via nitrosylation of cysteine residues in the transport ...
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Source: PubMed
Amino Acids 2020 Feb 01
Physicochemical properties of L- and DL-valine: first-principles calculations.
Fedorov I, Korabel'nikov D, Nguyen C, Prosekov A
At present, physicochemical properties of amino acid molecular crystals are of the utmost interest. The compounds where molecules have different chira ...
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Source: PubMed
Amino Acids 2020 Feb 01
Inhibition of antigen-specific immune responses by co-application of an indoleamine 2,3-dioxygenase (IDO)-encoding vector requires antigen transgene expression focused on dendritic cells.
Sudowe S, Höhn Y, Renzing A, Maxeiner J, Montermann E, Habermeier A, Closs E, Bros M, Reske-Kunz AB
We have previously shown that particle-mediated epidermal delivery (PMED) of plasmids encoding ß-galactosidase (ßGal) under control of the fascin-1 pr ...
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Source: PubMed