Nat Commun
Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.
Terashima Y, Toda E, Itakura M, Otsuji M, Yoshinaga S, Okumura K, Shand FHW, Komohara Y, Takeda M, Kokubo K, Chen MC, Yokoi S, Rokutan H, Kofuku Y, Ohnishi K, Ohira M, Iizasa T, Nakano H, Okabe T, Kojima H, Shimizu A, Kanegasaki S, Zhang MR, Shimada I, Nagase H, Terasawa H, Matsushima K
Tumor-associated macrophages affect tumor progression and resistance to immune checkpoint therapy. Here, we identify the chemokine signal regulator FR ...
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Source: PubMed
Neuropsychopharmacology 2020 Jan 29
Operant self-stimulation of thalamic terminals in the dorsomedial striatum is constrained by metabotropic glutamate receptor 2.
Johnson KA, Voyvodic L, Loewinger GC, Mateo Y, Lovinger DM
Dorsal striatal manipulations including stimulation of dopamine release and activation of medium spiny neurons (MSNs) are sufficient to drive reinforc ...
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Source: PubMed
J Biomed Opt
Measuring two-photon microscopy ultrafast laser pulse duration at the sample plane using time-correlated single-photon counting.
Kim Y, Vogel SS
<p>Two-photon microscopy (2PM) has revolutionized biomedical imaging by allowing thin optical sectioning in relatively thick biological specimens. Bec ...
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Source: PubMed
Addiction 2020 Jan 28
Commentary on Frost et al. (2019): The end of SBIRT and a new continuum of care.
Willenbring M
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Source: PubMed
Mayo Clin Proc Innov Qual Outcomes
Gastrointestinal Beriberi Mimicking a Surgical Emergency in a Well-Nourished Patient: A Case Report.
Vu TND, Junker MS, Kurjatko A, Albright RC, Heller SF, Rivera M
Beriberi is a well-documented disease caused by thiamine deficiency. The diagnosis of gastrointestinal beriberi in the clinical setting is uncommon, e ...
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Source: PubMed
