J. Alzheimers Dis. 2020 Jan 28
Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease.
Jääskeläinen O, Hall A, Tiainen M, van Gils M, Lötjönen J, Kangas AJ, Helisalmi S, Pikkarainen M, Hallikainen M, Koivisto A, Hartikainen P, Hiltunen M, Ala-Korpela M, Soininen P, Soininen H, Herukka SK
Accurate differentiation between neurodegenerative diseases is developing quickly and has reached an effective level in disease recognition. However, ...
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Source: PubMed
J. Alzheimers Dis. 2020 Jan 30
Altered Transcriptional Profile of Mitochondrial DNA-Encoded OXPHOS Subunits, Mitochondria Quality Control Genes, and Intracellular ATP Levels in Blood Samples of Patients with Parkinson's Disease.
Gezen-Ak D, Alaylioglu M, Genç G, Sengül B, Keskin E, Sordu P, Güleç ZEK, Apaydin H, Bayram-Gürel Ç, Ulutin T, Yilmazer S, Ertan S, Dursun E
Mitochondrial dysfunctions are significant contributors to neurodegeneration. One result or a cause of mitochondrial dysfunction might be the disrupti ...
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Source: PubMed
J. Alzheimers Dis. 2020 Jan 28
The Effect of Chronic Cerebral Hypoperfusion on Blood-Brain Barrier Permeability in a Transgenic Alzheimer's Disease Mouse Model (PS1V97L).
Yang H, Wang W, Jia L, Qin W, Hou T, Wu Q, Li H, Tian Y, Jia J
The blood-brain barrier (BBB) can restrict the therapeutic effects of Alzheimer's disease (AD) medications. While a large number of AD drug treatment ...
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Source: PubMed
J. Alzheimers Dis. 2020 Jan 28
Relationship of Established Cardiovascular Risk Factors and Peripheral Biomarkers on Cognitive Function in Adults at Risk of Cognitive Deterioration.
Lai MMY, Sharman MJ, Ames DJ, Ellis KA, Cox KL, Hepworth G, Desmond P, Cyarto EV, Martins RN, Masters CL, Lautenschlager NT
There is a paucity of information on the role of microvascular and inflammatory biomarkers in cognitive dysfunction. ...
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Source: PubMed
J. Alzheimers Dis. 2020 Jan 28
Elevated Urinary AD7c-NTP Levels in Older Adults with Hypertension and Cognitive Impairment.
Zhang Y, Li Y, Wang R, Sha G, Jin H, Ma L
Hypertension, a common chronic disease, is associated with cognitive impairment. Cognitive impairment, especially Alzheimer's disease (AD), seriously ...
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Source: PubMed
