Biol. Blood Marrow Transplant. 2020 Jan 30
Goal-oriented monitoring of cyclosporine is effective for graft-versus-host disease prevention after Hematopoietic Stem Cell Transplantation in Sickle Cell Disease and Thalassemia major.
Gauthier A, Bleyzac N, Garnier N, Kebaili K, Joly P, Goutagny MP, Mollet I, Goutelle S, Renard C, Bertrand Y
Graft-versus-host disease (GvHD) is an important challenge and one of the major causes of morbidity and mortality in children after hematopoietic stem ...
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Source: PubMed
J. Nutr. 2020 Jan 31
Lipid-Based Nutrient Supplementation Reduces Child Anemia and Increases Micronutrient Status in Madagascar: A Multiarm Cluster-Randomized Controlled Trial.
Stewart CP, Fernald LCH, Weber AM, Arnold C, Galasso E
Iron deficiency anemia affects hundreds of millions of women and children worldwide and is associated with impaired infant outcomes. Small-quantity li ...
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Source: PubMed
Am. J. Clin. Nutr. 2020 Feb 01
Delayed iron improves iron status without altering malaria risk in severe malarial anemia.
Cusick SE, Opoka RO, Ssemata AS, Georgieff MK, John CC
WHO guidelines recommend concurrent iron and antimalarial treatment in children with malaria and iron deficiency, but iron may not be well absorbed or ...
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Source: PubMed
Am. J. Hum. Genet. 2020 Jan 17
Bi-allelic Variants in TKFC Encoding Triokinase/FMN Cyclase Are Associated with Cataracts and Multisystem Disease.
Wortmann SB, Meunier B, Mestek-Boukhibar L, van den Broek F, Maldonado EM, Clement E, Weghuber D, Spenger J, Jaros Z, Taha F, Yue WW, Heales SJ, Davison JE, Mayr JA, Rahman S
We report an inborn error of metabolism caused by TKFC deficiency in two unrelated families. Rapid trio genome sequencing in family 1 and exome sequen ...
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Source: PubMed
Ann Diagn Pathol
Clinical impact of dysplastic changes in acquired aplastic anemia: A systematic study of bone marrow biopsies in children and adults.
Marchesi RF, Velloso EDRP, Garanito MP, Leal AM, Siqueira SAC, Azevedo Neto RS, Rocha V, Zerbini MCN
Aplastic anemia (AA) is a rare disorder characterized by suppression of bone marrow function, which can progress to myelodysplastic syndrome (MDS) or ...
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Source: PubMed
