Ther Innov Regul Sci
Investigation of Approval Trends and Benefits of New Fixed-Dose Combination Drugs in Japan.
Kikuchi C, Ohno M, Izumo T, Takahashi S, Aoki M, Shimomura H, Kawano Y, Shimada S, Aoyama T
New fixed-dose combination drugs (FDCs) had been developed in limited numbers in Japan. Since regulatory requirements were relaxed in 2005, 73 new FDC ...
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Source: PubMed
Amino Acids 2020 Feb 01
Inhibition of antigen-specific immune responses by co-application of an indoleamine 2,3-dioxygenase (IDO)-encoding vector requires antigen transgene expression focused on dendritic cells.
Sudowe S, Höhn Y, Renzing A, Maxeiner J, Montermann E, Habermeier A, Closs E, Bros M, Reske-Kunz AB
We have previously shown that particle-mediated epidermal delivery (PMED) of plasmids encoding ß-galactosidase (ßGal) under control of the fascin-1 pr ...
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Source: PubMed
Med. J. Malaysia
Recurrent bilateral eyelid and conjunctival granulomatosis in Churg-Strauss syndrome.
Jainuddin NF, Aliff IC, Chiew SF, Ramli N
A 47-year-old woman with poorly controlled asthma and allergic rhinitis presented with recurrent episodes of bilateral upper eyelid swelling associate ...
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Source: PubMed
Cytokine
Rosuvastatin suppresses cytokine production and lung inflammation in asthmatic, hyperlipidemic and asthmatic-hyperlipidemic rat models.
Saadat S, Mohamadian Roshan N, Aslani MR, Boskabady MH
Given the role that T lymphocytes play on the pathogenesis of allergic asthma, drugs targeting Th2 and Th17 cells may be a hopeful therapeutic strateg ...
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Source: PubMed
Int. Immunopharmacol.
Long-term methylglyoxal intake aggravates murine Th2-mediated airway eosinophil infiltration.
Medeiros ML, de Oliveira MG, Tavares EG, Mello GC, Anhê GF, Mónica FZ, Antunes E
Asthma outcomes is aggravated in obese patients. Excess of methylglyoxal (MGO) in obese/diabetic patients has been associated with diverse detrimental ...
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Source: PubMed
