Ther Innov Regul Sci
Investigation of Approval Trends and Benefits of New Fixed-Dose Combination Drugs in Japan.
Kikuchi C, Ohno M, Izumo T, Takahashi S, Aoki M, Shimomura H, Kawano Y, Shimada S, Aoyama T
New fixed-dose combination drugs (FDCs) had been developed in limited numbers in Japan. Since regulatory requirements were relaxed in 2005, 73 new FDC ...
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Source: PubMed
J. Rheumatol. 2020 Feb 01
Outcomes and safety of TNF inhibitors in reactive arthritis: A nationwide experience from Iceland.
Thorsteinsson B, Geirsson AJ, Krogh NS, Gudbjornsson B
Reactive arthritis (ReA) is a spondyloarthritis triggered by a bacterial infection. In cases where nonsteroidal anti-inflammatory drugs and convention ...
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Source: PubMed
Biomed. Pharmacother.
Grape seed proanthocyanidin extract reverses multidrug resistance in HL-60/ADR cells via inhibition of the PI3K/Akt signaling pathway.
Lin KN, Jiang YL, Zhang SG, Huang SY, Li H
Multidrug resistance (MDR) is a great challenge and obstacle in cancer treatment. It is a common problem in the treatment of acute myeloid leukemia (A ...
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Source: PubMed
Rev Port Cardiol 2020 Jan 29
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: Contemporaneous Portuguese cross-sectional data.
Caldeira D, Pereira H, Marques A, Alegria S, Calisto J, Silva PCD, Ribeiro VG, Silva JC, Seixo F, Abreu PFE, Teles RC, Fernandes R, Carvalho HC
The standard of care for acute ST-elevation myocardial infarction (STEMI) includes the activation of a STEMI care network, the administration of adjuv ...
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Source: PubMed
Epilepsy Behav
Antiepileptic drug effects on subjective and objective cognition.
Quon RJ, Mazanec MT, Schmidt SS, Andrew AS, Roth RM, MacKenzie TA, Sajatovic M, Spruill T, Jobst BC
Cognitive impairment is one of the most common complaints for persons with epilepsy (PWE). These impairments are not only associated with seizures, bu ...
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Source: PubMed
