Biochim Biophys Acta Rev Cancer 2020 Jan 30
Application of organoids in translational research of human diseases with a particular focus on gastrointestinal cancers.
Nguyen R, Bae SDW, Zhou G, Read S, Ahlenstiel G, George J, Qiao L
Gastrointestinal (GI) cancers constitute the largest portion of all human cancers and represent a significant health burden on modern society. Convent ...
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Source: PubMed
J. Hepatol.
Novel patient-derived preclinical models of liver cancer.
Bresnahan E, Ramadori P, Heikenwalder M, Zender L, Lujambio A
Preclinical models of cancer based on the use of human cancer cell lines and mouse models have enabled discoveries that have been successfully transla ...
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Source: PubMed
Naunyn Schmiedebergs Arch. Pharmacol. 2020 Jan 16
Enhanced anticancer activity of combined treatment of imatinib and dipyridamole in solid Ehrlich carcinoma-bearing mice.
El-Sisi AE, Sokar SS, Ibrahim HA, Abu-Risha SE
The current study was designed to evaluate potential enhancement of the anticancer activity of imatinib mesylate (IM) with dipyridamole (DIP) and to i ...
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Source: PubMed
NMR Biomed 2020 Jan 10
Inherently decoupled 1 H antennas and 31 P loops for metabolic imaging of liver metastasis at 7 T.
Rivera D, Kalleveen I, de Castro CA, van Laarhoven H, Klomp D, van der Kemp W, Stoker J, Nederveen A
High field 31 P spectroscopy has thus far been limited to diffuse liver disease. Unlike lower field-strength scanners, there is no body coil in the bo ...
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Source: PubMed
Cells
Dissimilar Appearances Are Deceptive-Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma.
Linck-Paulus L, Hellerbrand C, Bosserhoff AK, Dietrich P
: In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven ...
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Source: PubMed
