J. Food Biochem. 2020 Jan 14
Ketogenic diets and protective mechanisms in epilepsy, metabolic disorders, cancer, neuronal loss, and muscle and nerve degeneration.
Li RJ, Liu Y, Liu HQ, Li J
Ketogenic diet (KD), the "High-fat, low-carbohydrate, adequate-protein" diet strategy, replacing glucose with ketone bodies, is effective against seve ...
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Source: PubMed
Neurobiol. Dis.
Insulin deficiency promotes formation of toxic amyloid-ß42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.
Imamura T, Yanagihara YT, Ohyagi Y, Nakamura N, Iinuma KM, Yamasaki R, Asai H, Maeda M, Murakami K, Irie K, Kira JI
The toxic conformer of amyloid ß-protein (Aß) ending at 42 (Aß42), which contains a unique turn conformation at amino acid residue positions 22 and 23 ...
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Source: PubMed
Neurobiol. Aging 2019 Nov 27
A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice.
Yeh SH, Shie FS, Liu HK, Yao HH, Kao PC, Lee YH, Chen LM, Hsu SM, Chao LJ, Wu KW, Shiao YJ, Tsay HJ
High-fat and high-sugar diets contribute to the prevalence of type 2 diabetes and Alzheimer's disease (AD). Although the impact of high-fat diets on A ...
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Source: PubMed
Mol Nutr Food Res
DietaryAdvancedGlycationEnd Products-InducedCognitive Impairment in Aged ICR Mice: Protective Role of Quercetin.
Yang S, Wang G, Ma ZF, Qin LQ, Zhai YJ, Yu ZL, Xue M, Zhang YH, Wan Z
Dietary advanced glycation products (dAGEs) have been reported to induce cognitive impairment while quercetin possesses potential neuroprotective effe ...
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Source: PubMed
Nutrition
Effect of ultra-processed diet on gut microbiota and thus its role in neurodegenerative diseases.
Martínez Leo EE, Segura Campos MR
The current dietary pattern is characterized by high consumption of ultra-processed foods and lower consumption of fiber and vegetables, environmental ...
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Source: PubMed