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Latest Publications and Research on Diet and Alzheimer´s Disease

J. Food Biochem.   2020 Jan 14   

Ketogenic diets and protective mechanisms in epilepsy, metabolic disorders, cancer, neuronal loss, and muscle and nerve degeneration.

Li RJ, Liu Y, Liu HQ, Li J

Ketogenic diet (KD), the "High-fat, low-carbohydrate, adequate-protein" diet strategy, replacing glucose with ketone bodies, is effective against seve ... Read More

Source: PubMed
Neurobiol. Dis.      

Insulin deficiency promotes formation of toxic amyloid-ß42 conformer co-aggregating with hyper-phosphorylated tau oligomer in an Alzheimer's disease model.

Imamura T, Yanagihara YT, Ohyagi Y, Nakamura N, Iinuma KM, Yamasaki R, Asai H, Maeda M, Murakami K, Irie K, Kira JI

The toxic conformer of amyloid ß-protein (Aß) ending at 42 (Aß42), which contains a unique turn conformation at amino acid residue positions 22 and 23 ... Read More

Source: PubMed
Neurobiol. Aging   2019 Nov 27   

A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice.

Yeh SH, Shie FS, Liu HK, Yao HH, Kao PC, Lee YH, Chen LM, Hsu SM, Chao LJ, Wu KW, Shiao YJ, Tsay HJ

High-fat and high-sugar diets contribute to the prevalence of type 2 diabetes and Alzheimer's disease (AD). Although the impact of high-fat diets on A ... Read More

Source: PubMed
Mol Nutr Food Res      

DietaryAdvancedGlycationEnd Products-InducedCognitive Impairment in Aged ICR Mice: Protective Role of Quercetin.

Yang S, Wang G, Ma ZF, Qin LQ, Zhai YJ, Yu ZL, Xue M, Zhang YH, Wan Z

Dietary advanced glycation products (dAGEs) have been reported to induce cognitive impairment while quercetin possesses potential neuroprotective effe ... Read More

Source: PubMed
Nutrition      

Effect of ultra-processed diet on gut microbiota and thus its role in neurodegenerative diseases.

Martínez Leo EE, Segura Campos MR

The current dietary pattern is characterized by high consumption of ultra-processed foods and lower consumption of fiber and vegetables, environmental ... Read More

Source: PubMed

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