Int J Cardiol Heart Vasc
Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies.
Li KHC, Lee S, Yin C, Liu T, Ngarmukos T, Conte G, Yan GX, Sy RW, Letsas KP, Tse G
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to ventricular arrhythmias and sudden cardiac death. Originally believed ...
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Source: PubMed
Temperature (Austin)
Brain temperature and its role in physiology and pathophysiology: Lessons from 20 years of thermorecording.
Kiyatkin EA
It is well known that temperature affects the dynamics of all physicochemical processes governing neural activity. It is also known that the brain has ...
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Source: PubMed
Drug Saf 2020 Jan 06
Spontaneous Fluctuations in Liver Biochemistries in Patients with Compensated NASH Cirrhosis: Implications for Drug Hepatotoxicity Monitoring.
Shamseddeen H, Vilar-Gomez E, Chalasani N, Myers RP, Subramanian GM, Shlevin HH, Allgood AE, Orman ES
Patients with cirrhosis may have spontaneous fluctuations in liver enzymes, which may confound detection of drug-induced liver injury (DILI), but thes ...
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Source: PubMed
Psychopharmacology (Berl.) 2020 Jan 04
Lessons learned from using fMRI in the early clinical development of a mu-opioid receptor antagonist for disorders of compulsive consumption.
Nathan PJ, Bakker G
Functional magnetic resonance imaging (fMRI) has been widely used to gain a greater understanding of brain circuitry abnormalities in CNS disorders. f ...
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Source: PubMed
Pharmacol Res Perspect
LCAT protects against Lipoprotein-X formation in a murine model of drug-induced intrahepatic cholestasis.
Amar MJA, Freeman LA, Nishida T, Sampson ML, Pryor M, Vaisman BL, Neufeld EB, Karathanasis SK, Remaley AT
Familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease characterized by low HDL-C levels, low plasma choleste ...
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Source: PubMed
