Annu. Rev. Med.
Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity, and Stromal Inflammation.
Cook SA, Schafer S
Interleukin (IL)-11 is upregulated in a wide variety of fibro-inflammatory diseases such as systemic sclerosis, rheumatoid arthritis, pulmonary fibros ...
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Source: PubMed
Nat Commun
Structure-guided design of pure orthosteric inhibitors of aIIbß3 that prevent thrombosis but preserve hemostasis.
Adair BD, Alonso JL, van Agthoven J, Hayes V, Ahn HS, Yu IS, Lin SW, Xiong JP, Poncz M, Arnaout MA
A prevailing dogma is that inhibition of vascular thrombosis by antagonizing platelet integrin aIIbß3 cannot be achieved without compromising hemostas ...
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Source: PubMed
Pharm. Res.
Efficacy of Optimized Treatment Protocol Using LAU-7b Formulation against Ovalbumin (OVA) and House Dust Mite (HDM) -Induced Allergic Asthma in Atopic Hyperresponsive A/J Mice.
Youssef M, De Sanctis JB, Kanagaratham C, Tao S, Ahmed E, Radzioch D
To assess the efficacy of the novel clinical formulation of fenretinide (LAU-7b) for the treatment of allergic asthma. To study the association betwee ...
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Source: PubMed
Cureus
Unexpected Outcome of Daptomycin-induced Eosinophilic Pneumonia: Rarity Within a Rarity.
Raza A, Arslan A, Atiq MU, Chan V, Patel RK
Eosinophilic pneumonia comprises a group of lung diseases in which eosinophils appear in increased numbers in the lungs and sometimes in the bloodstre ...
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Source: PubMed
Yakugaku Zasshi
[Investigation of Drug-induced Lung Injury for the Development of a Novel Therapeutic Approach].
Kawami M
The development of serious lung diseases, such as pulmonary fibrosis, is associated with several drugs. A recent study has shown that the epithelial-m ...
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Source: PubMed
