Anal Bioanal Chem 2020 Feb 01
Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5a-reductase inhibitors.
Zheng R, Li L, Deng X, Tian M, Wang Z, Yang L
The 5a-reductase converts testosterone to dihydrotestosterone (DHT), and excess DHT could cause androgen-related diseases such as androgenetic alopeci ...
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Source: PubMed
Urology 2020 Jan 20
Efficacy and safety of 1470-nm Diode Laser Enucleation of the Prostate in Individuals with Benign Prostatic Hyperplasia Continuously Administered Oral Anticoagulants or Antiplatelet Drugs.
Zhang J, Li J, Wang X, Shi C, Tu M, Shi G
To evaluate the efficacy and safety of 1470-nm Diode Laser Enucleation of the Prostate (DiLEP) in patients with benign prostatic hyperplasia (BPH) con ...
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Source: PubMed
Int J Clin Exp Pathol
Hypoxia-inducible factor 1a (HIF-1a) mediates the epithelial-mesenchymal transition in benign prostatic hyperplasia.
Chen Y, Xu H, Shi Q, Gu M, Wan X, Chen Q, Wang Z
Epithelial-mesenchymal transition (EMT) based cancer cell invasion and metastasis has been thoroughly studied in prostate cancer. It was well known th ...
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Source: PubMed
Pharmazie
Evaluation of syncope association with a1-adrenoceptor blockers in males using the FAERS database: impact of concomitant hypertension.
Ohyama K, Hori Y, Sugiura M
Previous studies have revealed an association between the administration of a1-adrenoceptor blockers (a1Bs) and episodes of syncope in patients with b ...
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Source: PubMed
Pharmaceutics
In Vitro and In Vivo Assessment of Metabolic Drug Interaction Potential of Dutasteride with Ketoconazole.
Seo SW, Park JW, Han DG, Kim JM, Kim S, Park T, Kang KH, Yang MH, Yoon IS
Dutasteride (DUT) is a selective, potent, competitive, and irreversible inhibitor of both type-1 and type-2 5a-reductase (5AR) commonly used in the tr ...
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Source: PubMed
