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Latest Publications and Research on Drug Toxicity

Curr Oncol Rep      

Antibody-Drug Conjugates in Urothelial Carcinomas.

Sarfaty M, Rosenberg JE

Urothelial carcinoma (UC) is a common malignancy with an urgent need for more effective and less toxic treatment strategies. Antibody-drug conjugate ( ... Read More

Source: PubMed
Chemosphere      

The physiological and toxicological effects of antibiotics on an interspecies insect model.

Li G, Xia X, Zhao S, Shi M, Liu F, Zhu Y

Silkworm (Bombyx mori L.) has a clear genetic background, parts of which are highly homologous to certain genes related to human hereditary diseases. ... Read More

Source: PubMed
J. Inorg. Biochem.      

Synthesis, crystal structure and leishmanicidal activity of new trimethoprim Ru(III), Cu(II) and Pt(II) metal complexes.

Silva GL, Dias JSM, Silva HVR, Teixeira JDS, De Souza IRB, Guimarães ET, de Magalhães Moreira DR, Soares MBP, Barbosa MIF, Doriguetto AC

Leishmaniasis is a parasitic disease caused by protozoa of the genus Leishmania, which has very limited treatment options and affects poor and underde ... Read More

Source: PubMed
Int J Pharm   2020 Jan 30   

Synthesis of multimodal polymersomes for targeted drug delivery and MR/fluorescence imaging in metastatic breast cancer model.

Zavvar T, Babaei M, Abnous K, Mohammad Taghdisi S, Nekooei S, Ramezani M, Alibolandi M

The objective of the current study is to design and delivery of targeted PEG-PCL nanopolymersomes encapsulated with Gadolinium based Quantum Dots (QDs ... Read More

Source: PubMed
Eur J Pharm Biopharm   2020 Jan 30   

Coupling quaternary ammonium surfactants to the surface of liposomes improves both antibacterial efficacy and host cell biocompatibility.

Montefusco-Pereira CV, Formicola B, Goes A, Re F, Marrano CA, Mantegazza F, Carvalho-Wodarz C, Fuhrmann G, Caneva E, Nicotra F, Lehr CM, Russo L

By functionalizing the surface of PEG-liposomes with linkers bearing quaternary ammonium compounds (QACs), we generated novel bacteria disruptors with ... Read More

Source: PubMed

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