Nat Commun
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Pradas-Juni M, Hansmeier NR, Link JC, Schmidt E, Larsen BD, Klemm P, Meola N, Topel H, Loureiro R, Dhaouadi I, Kiefer CA, Schwarzer R, Khani S, Oliverio M, Awazawa M, Frommolt P, Heeren J, Scheja L, Heine M, Dieterich C, Büning H, Yang L, Cao H, Jesus DF, Kulkarni RN, Zevnik B, Tröder SE, Knippschild U, Edwards PA, Lee RG, Yamamoto M, Ulitsky I, Fernandez-Rebollo E, Vallim TQA, Kornfeld JW
Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in met ...
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Source: PubMed
J. Nutr. Biochem.
Maternal diets enriched in olive oil regulate lipid metabolism and levels of PPARs and their coactivators in the fetal liver in a rat model of gestational diabetes mellitus.
Fornes D, Gomez Ribot D, Heinecke F, Roberti SL, Capobianco E, Jawerbaum A
In a rat model of gestational diabetes mellitus (GDM) programmed in the offspring of neonatal streptozotocin-induced (nSTZ) diabetic rats, lipids are ...
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Source: PubMed
Pharmacol Rep
Reduction of cardiac and renal dysfunction by new inhibitor of DPP4 in diabetic rats.
Alves BEO, de Alencar AKN, Gamba LER, Trachez MM, da Silva JS, Araújo JSC, Montagnoli TL, Mendes LVP, Pimentel-Coelho PM, Cunha VDMN, Mendez-Otero R, Oliveira GMM, Lima LM, Barreiro EJ, Sudo RT, Zapata-Sudo G
Increased mortality due to type 2 diabetes mellitus (T2DM) has been associated with renal and/or cardiovascular dysfunction. Dipeptidyl dipeptidase-4 ...
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Source: PubMed
Pharmacol Rep
Hepatoprotective potential of 7,8-Dihydroxyflavone against alcohol and high-fat diet induced liver toxicity via attenuation of oxido-nitrosative stress and NF-?B activation.
Kumar D, Dwivedi DK, Lahkar M, Jangra A
Fatty liver diseases are the most common and major health concern arises from the modern lifestyle and alcohol (ethanol) abuse. The prevalence of non- ...
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Source: PubMed
J Clin Biochem Nutr
Trapa bispinosa Roxb. and lutein ameliorate cataract in type 1 diabetic rats.
Kinoshita S, Sugawa H, Nanri T, Ohno RI, Shirakawa JI, Sato H, Katsuta N, Sakake S, Nagai R
Trapa bispinosa Roxb. is an annual aquatic grass of the citrus family. Although its hot water extract displays antioxidative activity in vitro, little ...
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Source: PubMed
