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Latest Publications and Research on Genetics of Alzheimer´s disease

J Am Med Dir Assoc   2020 Jan 27   

Specific Nutritional Biomarker Profiles in Mild Cognitive Impairment and Subjective Cognitive Decline Are Associated With Clinical Progression: The NUDAD Project.

de Leeuw FA, van der Flier WM, Tijms BM, Scheltens P, Mendes VM, Manadas B, Bierau J, van Wijk N, van den Heuvel EGHM, Mohajeri MH, Teunissen CE, Kester MI

Nutritional insufficiencies have been associated with cognitive impairment. Understanding whether nutritional biomarker levels are associated with cli ... Read More

Source: PubMed
Curr Neuropharmacol   2020 Jan 28   

Alzheimer's Disorder: Epigenetic connection and associated risk factors.

Sharma VK, Mehta V, Singh TG

The gene based therapeutics and drug targets have shown incredible and appreciable advances in alleviating human sufferings and complexities. Epigenet ... Read More

Source: PubMed
Genomics   2020 Jan 23   

The relationship between the minor allele content and Alzheimer's disease.

Chen H, Lei X, Yuan D, Huang S

Alzheimer's disease (AD) is a chronic neurodegenerative disease. The genetic risk factors of AD remain better understood. Using previously published d ... Read More

Source: PubMed
PLoS Med.      

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study.

Mahajan UV, Varma VR, Griswold ME, Blackshear CT, An Y, Oommen AM, Varma S, Troncoso JC, Pletnikova O, O'Brien R, Hohman TJ, Legido-Quigley C, Thambisetty M

There is growing evidence that Alzheimer disease (AD) is a pervasive metabolic disorder with dysregulation in multiple biochemical pathways underlying ... Read More

Source: PubMed
Nat Commun      

FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease.

Yan T, Liang J, Gao J, Wang L, Fujioka H, Zhu X, Wang X

Alzheimer's disease (AD) is characterized by amyloid plaques and progressive cerebral atrophy. Here, we report FAM222A as a putative brain atrophy sus ... Read More

Source: PubMed
J Am Med Dir Assoc   2020 Jan 27   

Specific Nutritional Biomarker Profiles in Mild Cognitive Impairment and Subjective Cognitive Decline Are Associated With Clinical Progression: The NUDAD Project.

de Leeuw FA, van der Flier WM, Tijms BM, Scheltens P, Mendes VM, Manadas B, Bierau J, van Wijk N, van den Heuvel EGHM, Mohajeri MH, Teunissen CE, Kester MI

Nutritional insufficiencies have been associated with cognitive impairment. Understanding whether nutritional biomarker levels are associated with cli ... Read More

Source: PubMed
Curr Neuropharmacol   2020 Jan 28   

Alzheimer's Disorder: Epigenetic connection and associated risk factors.

Sharma VK, Mehta V, Singh TG

The gene based therapeutics and drug targets have shown incredible and appreciable advances in alleviating human sufferings and complexities. Epigenet ... Read More

Source: PubMed
Genomics   2020 Jan 23   

The relationship between the minor allele content and Alzheimer's disease.

Chen H, Lei X, Yuan D, Huang S

Alzheimer's disease (AD) is a chronic neurodegenerative disease. The genetic risk factors of AD remain better understood. Using previously published d ... Read More

Source: PubMed
PLoS Med.      

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and transcriptomic study.

Mahajan UV, Varma VR, Griswold ME, Blackshear CT, An Y, Oommen AM, Varma S, Troncoso JC, Pletnikova O, O'Brien R, Hohman TJ, Legido-Quigley C, Thambisetty M

There is growing evidence that Alzheimer disease (AD) is a pervasive metabolic disorder with dysregulation in multiple biochemical pathways underlying ... Read More

Source: PubMed
Nat Commun      

FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease.

Yan T, Liang J, Gao J, Wang L, Fujioka H, Zhu X, Wang X

Alzheimer's disease (AD) is characterized by amyloid plaques and progressive cerebral atrophy. Here, we report FAM222A as a putative brain atrophy sus ... Read More

Source: PubMed

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