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Latest Publications and Research on HCV Drug Treatment - New Frontiers

J. Clin. Virol.      

Community viral load and hepatitis C virus infection: Community viral load measures to aid public health treatment efforts and program evaluation.

Jordan AE, Perlman DC, Cleland CM, Wyka K, Schackman BR, Nash D

Hepatitis C virus (HCV) infection is the most prevalent blood-borne infection and causes more deaths than any other infectious disease in the US. Inci ... Read More

Source: PubMed
Atherosclerosis      

Impact of hepatitis C virus clearance by direct-acting antiviral treatment on the incidence of major cardiovascular events: A prospective multicentre study.

Adinolfi LE, Petta S, Fracanzani AL, Coppola C, Narciso V, Nevola R, Rinaldi L, Calvaruso V, Staiano L, Di Marco V, Marrone A, Pafundi PC, Solano A, Lombardi R, Sasso FC, Saturnino M, Rini F, Guerrera B, Troina G, Giordano M, Craxì A

HCV is associated with an increased risk of cardiovascular events (CV). Whether HCV clearance by direct-acting antivirals (DAA) reduces incident CV di ... Read More

Source: PubMed
Sex Transm Dis   2020 Jan 30   

Enhancing the Routine Screening Infrastructure to Address a Syphilis Epidemic in Miami-Dade County.

Venegas AL, Melbourne HM, Castillo IA, Spell K, Duquette W, Villamizar K, Gallo G, Parris D, Rojas LM

In a recent Sexually Transmitted Disease (STD) surveillance report from the Centers for Disease Control and Prevention (CDC), Miami-Dade County had th ... Read More

Source: PubMed
Expert Opin Drug Metab Toxicol   2020 Jan 31   

PK/PD and antiviral activity of anti-HCV therapy: is there still a role in the choice of treatment?

Zuccaro V, Lombardi A, Asperges E, Sacchi P, Bruno R

Introduction: Despite the high rate of response, the treatment of special populations, the management of patients with previous failure to direct-acti ... Read More

Source: PubMed
Nat Commun      

Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection.

Barili V, Fisicaro P, Montanini B, Acerbi G, Filippi A, Forleo G, Romualdi C, Ferracin M, Guerrieri F, Pedrazzi G, Boni C, Rossi M, Vecchi A, Penna A, Zecca A, Mori C, Orlandini A, Negri E, Pesci M, Massari M, Missale G, Levrero M, Ottonello S, Ferrari C

Hepatitis C virus infection (HCV) represents a unique model to characterize, from early to late stages of infection, the T cell differentiation proces ... Read More

Source: PubMed
J. Clin. Virol.      

Community viral load and hepatitis C virus infection: Community viral load measures to aid public health treatment efforts and program evaluation.

Jordan AE, Perlman DC, Cleland CM, Wyka K, Schackman BR, Nash D

Hepatitis C virus (HCV) infection is the most prevalent blood-borne infection and causes more deaths than any other infectious disease in the US. Inci ... Read More

Source: PubMed
Atherosclerosis      

Impact of hepatitis C virus clearance by direct-acting antiviral treatment on the incidence of major cardiovascular events: A prospective multicentre study.

Adinolfi LE, Petta S, Fracanzani AL, Coppola C, Narciso V, Nevola R, Rinaldi L, Calvaruso V, Staiano L, Di Marco V, Marrone A, Pafundi PC, Solano A, Lombardi R, Sasso FC, Saturnino M, Rini F, Guerrera B, Troina G, Giordano M, Craxì A

HCV is associated with an increased risk of cardiovascular events (CV). Whether HCV clearance by direct-acting antivirals (DAA) reduces incident CV di ... Read More

Source: PubMed
Sex Transm Dis   2020 Jan 30   

Enhancing the Routine Screening Infrastructure to Address a Syphilis Epidemic in Miami-Dade County.

Venegas AL, Melbourne HM, Castillo IA, Spell K, Duquette W, Villamizar K, Gallo G, Parris D, Rojas LM

In a recent Sexually Transmitted Disease (STD) surveillance report from the Centers for Disease Control and Prevention (CDC), Miami-Dade County had th ... Read More

Source: PubMed
Expert Opin Drug Metab Toxicol   2020 Jan 31   

PK/PD and antiviral activity of anti-HCV therapy: is there still a role in the choice of treatment?

Zuccaro V, Lombardi A, Asperges E, Sacchi P, Bruno R

Introduction: Despite the high rate of response, the treatment of special populations, the management of patients with previous failure to direct-acti ... Read More

Source: PubMed
Nat Commun      

Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection.

Barili V, Fisicaro P, Montanini B, Acerbi G, Filippi A, Forleo G, Romualdi C, Ferracin M, Guerrieri F, Pedrazzi G, Boni C, Rossi M, Vecchi A, Penna A, Zecca A, Mori C, Orlandini A, Negri E, Pesci M, Massari M, Missale G, Levrero M, Ottonello S, Ferrari C

Hepatitis C virus infection (HCV) represents a unique model to characterize, from early to late stages of infection, the T cell differentiation proces ... Read More

Source: PubMed
J. Clin. Virol.      

Community viral load and hepatitis C virus infection: Community viral load measures to aid public health treatment efforts and program evaluation.

Jordan AE, Perlman DC, Cleland CM, Wyka K, Schackman BR, Nash D

Hepatitis C virus (HCV) infection is the most prevalent blood-borne infection and causes more deaths than any other infectious disease in the US. Inci ... Read More

Source: PubMed
Atherosclerosis      

Impact of hepatitis C virus clearance by direct-acting antiviral treatment on the incidence of major cardiovascular events: A prospective multicentre study.

Adinolfi LE, Petta S, Fracanzani AL, Coppola C, Narciso V, Nevola R, Rinaldi L, Calvaruso V, Staiano L, Di Marco V, Marrone A, Pafundi PC, Solano A, Lombardi R, Sasso FC, Saturnino M, Rini F, Guerrera B, Troina G, Giordano M, Craxì A

HCV is associated with an increased risk of cardiovascular events (CV). Whether HCV clearance by direct-acting antivirals (DAA) reduces incident CV di ... Read More

Source: PubMed
Sex Transm Dis   2020 Jan 30   

Enhancing the Routine Screening Infrastructure to Address a Syphilis Epidemic in Miami-Dade County.

Venegas AL, Melbourne HM, Castillo IA, Spell K, Duquette W, Villamizar K, Gallo G, Parris D, Rojas LM

In a recent Sexually Transmitted Disease (STD) surveillance report from the Centers for Disease Control and Prevention (CDC), Miami-Dade County had th ... Read More

Source: PubMed
Expert Opin Drug Metab Toxicol   2020 Jan 31   

PK/PD and antiviral activity of anti-HCV therapy: is there still a role in the choice of treatment?

Zuccaro V, Lombardi A, Asperges E, Sacchi P, Bruno R

Introduction: Despite the high rate of response, the treatment of special populations, the management of patients with previous failure to direct-acti ... Read More

Source: PubMed
Nat Commun      

Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection.

Barili V, Fisicaro P, Montanini B, Acerbi G, Filippi A, Forleo G, Romualdi C, Ferracin M, Guerrieri F, Pedrazzi G, Boni C, Rossi M, Vecchi A, Penna A, Zecca A, Mori C, Orlandini A, Negri E, Pesci M, Massari M, Missale G, Levrero M, Ottonello S, Ferrari C

Hepatitis C virus infection (HCV) represents a unique model to characterize, from early to late stages of infection, the T cell differentiation proces ... Read More

Source: PubMed
J. Clin. Virol.      

Community viral load and hepatitis C virus infection: Community viral load measures to aid public health treatment efforts and program evaluation.

Jordan AE, Perlman DC, Cleland CM, Wyka K, Schackman BR, Nash D

Hepatitis C virus (HCV) infection is the most prevalent blood-borne infection and causes more deaths than any other infectious disease in the US. Inci ... Read More

Source: PubMed
Atherosclerosis      

Impact of hepatitis C virus clearance by direct-acting antiviral treatment on the incidence of major cardiovascular events: A prospective multicentre study.

Adinolfi LE, Petta S, Fracanzani AL, Coppola C, Narciso V, Nevola R, Rinaldi L, Calvaruso V, Staiano L, Di Marco V, Marrone A, Pafundi PC, Solano A, Lombardi R, Sasso FC, Saturnino M, Rini F, Guerrera B, Troina G, Giordano M, Craxì A

HCV is associated with an increased risk of cardiovascular events (CV). Whether HCV clearance by direct-acting antivirals (DAA) reduces incident CV di ... Read More

Source: PubMed
Sex Transm Dis   2020 Jan 30   

Enhancing the Routine Screening Infrastructure to Address a Syphilis Epidemic in Miami-Dade County.

Venegas AL, Melbourne HM, Castillo IA, Spell K, Duquette W, Villamizar K, Gallo G, Parris D, Rojas LM

In a recent Sexually Transmitted Disease (STD) surveillance report from the Centers for Disease Control and Prevention (CDC), Miami-Dade County had th ... Read More

Source: PubMed
Expert Opin Drug Metab Toxicol   2020 Jan 31   

PK/PD and antiviral activity of anti-HCV therapy: is there still a role in the choice of treatment?

Zuccaro V, Lombardi A, Asperges E, Sacchi P, Bruno R

Introduction: Despite the high rate of response, the treatment of special populations, the management of patients with previous failure to direct-acti ... Read More

Source: PubMed
Nat Commun      

Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection.

Barili V, Fisicaro P, Montanini B, Acerbi G, Filippi A, Forleo G, Romualdi C, Ferracin M, Guerrieri F, Pedrazzi G, Boni C, Rossi M, Vecchi A, Penna A, Zecca A, Mori C, Orlandini A, Negri E, Pesci M, Massari M, Missale G, Levrero M, Ottonello S, Ferrari C

Hepatitis C virus infection (HCV) represents a unique model to characterize, from early to late stages of infection, the T cell differentiation proces ... Read More

Source: PubMed

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