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Hirschsprung Disease / Congenital Megacolon

Latest Publications and Research on Hirschsprungs Disease

Neurogastroenterol. Motil.   2020 Jan 27   

Visualization of the human enteric nervous system by confocal laser endomicroscopy in Hirschsprung's disease: An alternative to intraoperative histopathological diagnosis?

Shimojima N, Kobayashi M, Kamba S, Harada A, Hirobe S, Ieiri S, Kuroda T, Sumiyama K

Hirschsprung's disease is a congenital abnormality of the enteric nervous system (ENS) presenting severe constipation soon after birth due to the lack ... Read More

Source: PubMed
An Pediatr (Barc)   2020 Jan 23   

[New mutations associated with Hirschsprung disease].

Lorente-Ros M, Andrés AM, Sánchez-Galán A, Amiñoso C, García S, Lapunzina P, Solera García J

Hirschsprung disease is caused by an impairment in cell migration from the neural crest to the gastrointestinal tract, resulting in an absence of neur ... Read More

Source: PubMed
Gut Microbes   2020 Jan 16   

Prospective study reveals a microbiome signature that predicts the occurrence of post-operative enterocolitis in Hirschsprung disease (HSCR) patients.

Tang W, Su Y, Yuan C, Zhang Y, Zhou L, Peng L, Wang P, Chen G, Li Y, Li H, Zhi Z, Chang H, Hang B, Mao JH, Snijders AM, Xia Y

Hirschsprung disease (HSCR) is a birth defect with an approximate incidence of 1/5,000 live births, and up to one-third of HSCR patients develop Hirsc ... Read More

Source: PubMed
J Laparoendosc Adv Surg Tech A   2020 Jan 14   

Laparoscopic-Assisted Transanal Pull-Through in Hirschsprung Disease: Does Laparoscopic Dissection Minimize Anal Overstretching?

Bawazir OA

Introduction: Surgical treatment for Hirschsprung disease (HD) has evolved from a staged repair to a primary operation but is still associated with si ... Read More

Source: PubMed

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