Nat Commun
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.
Pradas-Juni M, Hansmeier NR, Link JC, Schmidt E, Larsen BD, Klemm P, Meola N, Topel H, Loureiro R, Dhaouadi I, Kiefer CA, Schwarzer R, Khani S, Oliverio M, Awazawa M, Frommolt P, Heeren J, Scheja L, Heine M, Dieterich C, Büning H, Yang L, Cao H, Jesus DF, Kulkarni RN, Zevnik B, Tröder SE, Knippschild U, Edwards PA, Lee RG, Yamamoto M, Ulitsky I, Fernandez-Rebollo E, Vallim TQA, Kornfeld JW
Obesity and type 2 diabetes mellitus are global emergencies and long noncoding RNAs (lncRNAs) are regulatory transcripts with elusive functions in met ...
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Source: PubMed
Nutr Health 2020 Jan 30
Effects of a four-week very low-carbohydrate high-fat diet on biomarkers of inflammation: Non-randomised parallel-group study.
Cipryan L, Maffetone PB, Plews DJ, Laursen PB
It is commonly assumed that increased dietary fat and/or caloric excess induces chronic inflammatory processes, since the association between obesity ...
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Source: PubMed
Front Microbiol
Screening for Potential Novel Probiotics With Dipeptidyl Peptidase IV-Inhibiting Activity for Type 2 Diabetes Attenuation in vitro and in vivo.
Yan F, Li N, Yue Y, Wang C, Zhao L, Evivie SE, Li B, Huo G
Diabetes has become the second most severe disease to human health. Probiotics are important for maintaining gastrointestinal homeostasis and energy b ...
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Source: PubMed
Eur. J. Clin. Invest. 2020 Jan 29
Marked differences in prediabetes and diabetes associated comorbidities between men and women - epidemiological results from a general population-based cohort aged 6-80 years - the LEAD (Lung, hEart, sociAl, boDy) study.
Breyer MK, Ofenheimer A, Altziebler J, Hartl S, Burghuber OC, Studnicka M, Purin D, Heinzle C, Drexel H, Franssen FM, Wouters EF, Harreiter J, Kautzky-Willer A, Breyer-Kohansal R
Based on biological and behavioural diversity sex and gender may affect co-morbidities associated with prediabetes and diabetes. Besides evaluating th ...
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Source: PubMed
Sci Rep
Long-term metabolic consequences of acute dioxin exposure differ between male and female mice.
Hoyeck MP, Blair H, Ibrahim M, Solanki S, Elsawy M, Prakash A, Rick KRC, Matteo G, O'Dwyer S, Bruin JE
Epidemiological studies have consistently shown an association between exposure to environmental pollutants and diabetes risk in humans. We have previ ...
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Source: PubMed