PLoS ONE
Compartmentalized profiling of amniotic fluid cytokines in women with preterm labor.
Bhatti G, Romero R, Rice GE, Fitzgerald W, Pacora P, Gomez-Lopez N, Kavdia M, Tarca AL, Margolis L
Amniotic fluid cytokines have been implicated in the mechanisms of preterm labor and birth. Cytokines can be packaged within or on the surface of extr ...
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Source: PubMed
J Perinat Med
Microbial burden and inflammasome activation in amniotic fluid of patients with preterm prelabor rupture of membranes.
Theis KR, Romero R, Motomura K, Galaz J, Winters AD, Pacora P, Miller D, Slutsky R, Florova V, Levenson D, Para R, Varrey A, Kacerovsky M, Hsu CD, Gomez-Lopez N
Background Intra-amniotic inflammation, which is associated with adverse pregnancy outcomes, can occur in the presence or absence of detectable microo ...
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Source: PubMed
J. Matern. Fetal. Neonatal. Med. 2020 Jan 08
Clinical chorioamnionitis criteria are not sufficient for predicting intra-amniotic infection.
Maki Y, Furukawa S, Nakayama T, Oohashi M, Shiiba N, Furuta K, Tokunaga S, Sameshima H
Aim: To evaluate the diagnostic performance of three conventional clinical chorioamnionitis criteria; including Gibbs, Lencki, and suspected triple I; ...
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Source: PubMed
FASEB J. 2019 Dec 23
Prenatal inflammation suppresses blood Th1 polarization and gene clusters related to cellular energy metabolism in preterm newborns.
Ren S, Pan X, Gao F, Sangild PT, Nguyen DN
Chorioamnionitis (CA, fetal membrane inflammation) predisposes to preterm birth and is associated with increased neonatal infection risk, but the sepa ...
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Source: PubMed
J. Matern. Fetal. Neonatal. Med. 2019 Dec 29
Preterm labor is characterized by a high abundance of amniotic fluid prostaglandins in patients with intra-amniotic infection or sterile intra-amniotic inflammation.
Peiris HN, Romero R, Vaswani K, Reed S, Gomez-Lopez N, Tarca AL, Gudicha DW, Erez O, Maymon E, Mitchell MD
Objective: To distinguish between prostaglandin and prostamide concentrations in the amniotic fluid of women who had an episode of preterm labor with ...
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Source: PubMed