J. Am. Coll. Surg. 2020 Jan 30
Risk of Metachronous Colorectal Neoplasm After a Segmental Colectomy in Lynch Syndrome Patients According to Mismatch Repair Gene Status.
Quezada-Diaz FF, Hameed I, von Mueffling A, Salo-Mullen EE, Catalano JD, Smith JJ, Weiser MR, Garcia-Aguilar J, Stadler ZK, Guillem JG
Because of increased risk of metachronous colorectal cancer (CRC), all Lynch Syndrome (LS) patients are offered a total colectomy. However, since meta ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 30
Prevalence of CNV-neutral structural genomic rearrangements in MLH1, MSH2, and PMS2 not detectable in routine NGS diagnostics.
Morak M, Steinke-Lange V, Massdorf T, Benet-Pages A, Locher M, Laner A, Kayser K, Aretz S, Holinski-Feder E
Routine diagnostics for colorectal cancer patients suspected of having Lynch-Syndrome (LS) currently uses Next-Generation-Sequencing (NGS) of targeted ...
Read More
Source: PubMed
Front Immunol
Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer.
Ramchander NC, Ryan NAJ, Walker TDJ, Harries L, Bolton J, Bosse T, Evans DG, Crosbie EJ
Around 30% of endometrial cancers (EC) are mismatch repair (MMR) deficient, mostly as a consequence of mutations acquired during tumorigenesis, but a ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 29
Factors associated with decision-making on prophylactic hysterectomy and attitudes towards gynecological surveillance among women with Lynch syndrome (LS): a descriptive study.
Kalamo MH, Mäenpää JU, Seppälä TT, Mecklin JP, Huhtala H, Sorvettula K, Pylvänäinen K, Staff S
To prevent endometrial carcinoma in Lynch syndrome (LS), regular gynecological surveillance visits and prophylactic surgery are recommended. Previous ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 29
Detection of DNA mismatch repair deficient crypts in random colonoscopic biopsies identifies Lynch syndrome patients.
Brand RE, Dudley B, Karloski E, Das R, Fuhrer K, Pai RK, Pai RK
The hallmark of Lynch syndrome (LS)-associated neoplasia is DNA mismatch repair protein (MMR) deficiency. Recent studies have demonstrated that histol ...
Read More
Source: PubMed
J. Am. Coll. Surg. 2020 Jan 30
Risk of Metachronous Colorectal Neoplasm After a Segmental Colectomy in Lynch Syndrome Patients According to Mismatch Repair Gene Status.
Quezada-Diaz FF, Hameed I, von Mueffling A, Salo-Mullen EE, Catalano JD, Smith JJ, Weiser MR, Garcia-Aguilar J, Stadler ZK, Guillem JG
Because of increased risk of metachronous colorectal cancer (CRC), all Lynch Syndrome (LS) patients are offered a total colectomy. However, since meta ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 30
Prevalence of CNV-neutral structural genomic rearrangements in MLH1, MSH2, and PMS2 not detectable in routine NGS diagnostics.
Morak M, Steinke-Lange V, Massdorf T, Benet-Pages A, Locher M, Laner A, Kayser K, Aretz S, Holinski-Feder E
Routine diagnostics for colorectal cancer patients suspected of having Lynch-Syndrome (LS) currently uses Next-Generation-Sequencing (NGS) of targeted ...
Read More
Source: PubMed
Front Immunol
Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer.
Ramchander NC, Ryan NAJ, Walker TDJ, Harries L, Bolton J, Bosse T, Evans DG, Crosbie EJ
Around 30% of endometrial cancers (EC) are mismatch repair (MMR) deficient, mostly as a consequence of mutations acquired during tumorigenesis, but a ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 29
Factors associated with decision-making on prophylactic hysterectomy and attitudes towards gynecological surveillance among women with Lynch syndrome (LS): a descriptive study.
Kalamo MH, Mäenpää JU, Seppälä TT, Mecklin JP, Huhtala H, Sorvettula K, Pylvänäinen K, Staff S
To prevent endometrial carcinoma in Lynch syndrome (LS), regular gynecological surveillance visits and prophylactic surgery are recommended. Previous ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 29
Detection of DNA mismatch repair deficient crypts in random colonoscopic biopsies identifies Lynch syndrome patients.
Brand RE, Dudley B, Karloski E, Das R, Fuhrer K, Pai RK, Pai RK
The hallmark of Lynch syndrome (LS)-associated neoplasia is DNA mismatch repair protein (MMR) deficiency. Recent studies have demonstrated that histol ...
Read More
Source: PubMed
J. Am. Coll. Surg. 2020 Jan 30
Risk of Metachronous Colorectal Neoplasm After a Segmental Colectomy in Lynch Syndrome Patients According to Mismatch Repair Gene Status.
Quezada-Diaz FF, Hameed I, von Mueffling A, Salo-Mullen EE, Catalano JD, Smith JJ, Weiser MR, Garcia-Aguilar J, Stadler ZK, Guillem JG
Because of increased risk of metachronous colorectal cancer (CRC), all Lynch Syndrome (LS) patients are offered a total colectomy. However, since meta ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 30
Prevalence of CNV-neutral structural genomic rearrangements in MLH1, MSH2, and PMS2 not detectable in routine NGS diagnostics.
Morak M, Steinke-Lange V, Massdorf T, Benet-Pages A, Locher M, Laner A, Kayser K, Aretz S, Holinski-Feder E
Routine diagnostics for colorectal cancer patients suspected of having Lynch-Syndrome (LS) currently uses Next-Generation-Sequencing (NGS) of targeted ...
Read More
Source: PubMed
Front Immunol
Distinct Immunological Landscapes Characterize Inherited and Sporadic Mismatch Repair Deficient Endometrial Cancer.
Ramchander NC, Ryan NAJ, Walker TDJ, Harries L, Bolton J, Bosse T, Evans DG, Crosbie EJ
Around 30% of endometrial cancers (EC) are mismatch repair (MMR) deficient, mostly as a consequence of mutations acquired during tumorigenesis, but a ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 29
Factors associated with decision-making on prophylactic hysterectomy and attitudes towards gynecological surveillance among women with Lynch syndrome (LS): a descriptive study.
Kalamo MH, Mäenpää JU, Seppälä TT, Mecklin JP, Huhtala H, Sorvettula K, Pylvänäinen K, Staff S
To prevent endometrial carcinoma in Lynch syndrome (LS), regular gynecological surveillance visits and prophylactic surgery are recommended. Previous ...
Read More
Source: PubMed
Fam. Cancer 2020 Jan 29
Detection of DNA mismatch repair deficient crypts in random colonoscopic biopsies identifies Lynch syndrome patients.
Brand RE, Dudley B, Karloski E, Das R, Fuhrer K, Pai RK, Pai RK
The hallmark of Lynch syndrome (LS)-associated neoplasia is DNA mismatch repair protein (MMR) deficiency. Recent studies have demonstrated that histol ...
Read More
Source: PubMed
