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Metformin - Diabetes Drug with New Therapeutic Uses

Latest Publications and Research on Metformin - Diabetes Drug with New Therapeutic Uses

Diabetes Metab.   2020 Jan 30   

Reduction in HbA1c with SGLT2 inhibitors vs DPP-4 inhibitors as add-ons to metformin monotherapy according to baseline HbA1c: a systematic review of randomized controlled trials.

Scheen AJ

This study compared the reduction of glycated haemoglobin (HbA1c) with sodium-glucose cotransporter type-2 inhibitors (SGLT2is) vs dipeptidyl peptidas ... Read More

Source: PubMed
Diabetes Res. Clin. Pract.   2020 Jan 29   

Effectiveness, safety, and tolerability of vildagliptin or vildagliptin/metformin combination in patients with type 2 diabetes uncontrolled on insulin therapy in a real-world setting in Egypt: the OMEGA study.

El Ebrashy I, El Kafrawy N, Raouf R, Yousry D

To evaluate the effectiveness and safety of vildagliptin or vildagliptin/metformin combination among patients with type 2 diabetes mellitus (T2DM) unc ... Read More

Source: PubMed
Diabetes Res. Clin. Pract.   2020 Jan 29   

The beneficial effects (on cardio-renal system) of glucose-lowering agents with caloric-restriction mimetic properties are subtractive rather than additive.

Prattichizzo F

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Source: PubMed
Gut Microbes   2020 Jan 31   

Considering gut microbiota in treatment of type 2 diabetes mellitus.

Adeshirlarijaney A, Gewirtz AT

Advances in the understanding of the pathogenesis of type 2 diabetes mellitus (T2D) have revealed a role for gut microbiota dysbiosis in driving this ... Read More

Source: PubMed
Eur. J. Pharmacol.      

Infliximab ameliorates tumor necrosis factor-alpha exacerbated renal insulin resistance induced in rats by regulating insulin signaling pathway.

Mohamad HE, Asker ME, Keshawy MM, Abdel Aal SM, Mahmoud YK

Infliximab (IFX), a monoclonal antibody for tumor necrosis factor-alpha (TNF-a), is known to restore blood glucose homeostasis. However, its effects o ... Read More

Source: PubMed
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